Bulletin of Experimental Biology and Medicine

, Volume 125, Issue 1, pp 10–11 | Cite as

The role of salivary glands in the removal of excessive blood plasma norepinephrine

  • V. V. Mikhailov
  • M. A. Gordeeva
  • V. N. Matveeva


Standard high-performance liquid chromatography was used to study the contents of epinephrine and norepinephrine in rat submaxillary salivary glands, oral cavity mucosa, and in saliva during background and evoked secretion as well as in plasma after parenteral injection of norepinephrine solution. The pilocarpine-induced stimulation of secretory function of the salivary glands increases epinephrine content in the oral cavity mucosa, while in the salivary gland its concentration decreases, although the norepinephrine content remains at the control level. The concentrations of these amines do not vary in saliva, but their release with saliva increases. Presumably, the salivary glands accumulate and release catecholamines during the secretion cycle.

Key Words

salivary glands catecholamines oral cavity mucosa 


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Copyright information

© Plenum Publishing Corporation 1998

Authors and Affiliations

  • V. V. Mikhailov
    • 1
  • M. A. Gordeeva
    • 1
  • V. N. Matveeva
    • 1
  1. 1.Department of Pathological Physiology, Therapeufical FacultyMoscow Medical Institute of DentistryMoscowUSSR

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