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Mixture of closely related isomeric triterpenoid derivatives: Separation and purification by reversed-phase high-performance liquid chromatography

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Summary

Twelve triterpenes were isolated from the alcoholic extract ofMentha villosa as their acetyl methyl ester derivatives. This vegetal specimen, which was collected in the Horto de Plantas Medicinais da Universidade Federal do Ceará, Fortaleza, Brazil, is used as popular remedy in the treatment of amebiasis, giardiasis and shistosomiasis. The separation and purification of the triterpenoid derivatives from complex mixtures of closely related isomeric triterpenoid acids has been performed successfully by reversed-phase HPLC.

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Authors and Affiliations

  1. Departamento de Química Orgânica e Inorgânica, Universidade Federal do Ceará, Cx. Postal 12200, 60021-970, Fortaleza-CE, Brazil

    F. J. Q. Monte

  2. Laboratoire de RMN et de Modelisation Moléculaire, UA 422 du CNRS, Faculté de Chimie, Université Louis Pauster, 67008, Strasbourg, France

    J. P. Kintzinger

  3. Laboratoire de Géochimie Organique, Université Louis Pauster, 67008, Strasbourg, France

    J. M. Trendel & J. Poinsot

Authors
  1. F. J. Q. Monte
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  2. J. P. Kintzinger
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  3. J. M. Trendel
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  4. J. Poinsot
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Monte, F.J.Q., Kintzinger, J.P., Trendel, J.M. et al. Mixture of closely related isomeric triterpenoid derivatives: Separation and purification by reversed-phase high-performance liquid chromatography. Chromatographia 46, 251–255 (1997). https://doi.org/10.1007/BF02496315

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  • DOI: https://doi.org/10.1007/BF02496315

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