Russian Chemical Bulletin

, Volume 46, Issue 6, pp 1178–1179 | Cite as

Synthesis of acetonylmalonaldehyde and its interaction with aminoazoles

  • M. M. Vartanyan
  • O. L. Eliseev
  • Kh. R. Skov
  • R. A. Karakhanov
Brief Communications


Acetonylmalonaldehyde (1) was obtained for the first time by hydrolysis of 2,5-dimethoxy-5-methyltetrahydrofuran-3-carbaldehyde. The interaction of1 with 3-amino-5-methylpyrazole, 3-amino-1,2,4-triazole, 2-aminobenzimidazole, and 5-aminotetrazole results in the formation of functionally substituted azolopyrimidines.

Key words

tetrahydrofurans, hydrolysis acetonylmalonaldehyde, aminoazoles, reaction 


  1. 1.
    A. V. Khandin, M. M. Vartanyan, and L. Yu. Brezhnev,Izv. Akad. Nauk SSSR, Ser. Khim., 1989, 2389 [Bull. Acad. Sci. USSR, Div. Chem. Sci., 1989,38, 2200 (Engl. Transl.)].Google Scholar
  2. 2.
    M. M. Vartanyan, O. L. Eliseev, T. Yu. Solov'eva, B. I. Ugrak, and Kh. R. Skov,Izv. Akad. Nauk, Ser. Khim., 1994, 1997 [Russ. Chem. Bull., 1994,43, 1884 (Engl. Transl.)].Google Scholar
  3. 3.
    N. N. Shapet'ko, A. V. Kessenikh, A. P. Skoldinov, and T. V. Protopopova,Teor. Eksp. Khim., 1966,2, 757 [Theor. Exp. Chem., 1966,2 (Engl. Transl.)].Google Scholar

Copyright information

© Plenum Publishing Corporation 1997

Authors and Affiliations

  • M. M. Vartanyan
    • 1
  • O. L. Eliseev
    • 1
  • Kh. R. Skov
    • 2
  • R. A. Karakhanov
    • 3
  1. 1.N. D. Zelinsky Institute of Organic ChemistryRussian Academy of SciencesMoscowRussian Federation
  2. 2.Hexagon CompanyCopenhagenDenmark
  3. 3.I. M. Gubkin State Academy of Oil and GasMoscowRussian Federation

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