Abstract
4-Methoxy-1,1,1-trifluoropent-3-en-2-one reacts with cyanothioacetamide to give 3-cyano-4-methyl-6-trifluoromethylpyridine-2(1H)-thione, which was transformed into 3-amino-4-methyl-6-trifluoromethylthieno[2,3-b]pyridine-2-carboxanilide by the reaction with chloroacetanilide. The crystal and molecular structure of the amide obtained was studied by X-ray analysis.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
K.G. Nikishin, V. P. Kislyi, V. N. Nesterov, A. M. Shestopalov, Yu. T. Struchkov, and V. V. Semenov,Izv. Akad. Nauk, Ser. Khim., 1998, 482 [Russ. Chem. Bull., 1998,47, 465 (Engl. Transl.)].
A. Bondi,J. Phys. Chem., 1964,68, 441.
R. Taylor and O. Kennard,J. Am. Chem. Soc., 1982,104, 5063.
L. Berkovitch-Yellin and L. Leiserowitz,Acta Crystallogr., 1984,B40, 159.
F. H. Allen, O. Kennard, D. G. Watson, L. Brammer, A. G. Orpen, and R. Taylor,J. Chem. Soc., Perkin Trans. 2, 1987, 1.
W. Robinson, inCrystallographic Computing—Techniques and New Technologies, Oxford Univ. Press, Oxford, 1988, 366.
Author information
Authors and Affiliations
Additional information
Translated fromIzvestiya Akademii Nauk Seriya Khimicheskaya, No. 4, pp. 701–703, April, 1998.
Rights and permissions
About this article
Cite this article
Nikishin, K.G., Nesterov, V.N., Kislyi, V.P. et al. Synthesis of 3-amino-4-methyl-6-trifluoromethylthieno[2,3-b]pyridine-2-carboxanilide and its crystal and molecular structure. Russ Chem Bull 47, 679–681 (1998). https://doi.org/10.1007/BF02495978
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1007/BF02495978