Abstract
β-Aminopropionohydroxamic acid reacts with aliphatic aldehydes or ketones to give 2-substituted 1-hydroxytetrahydropyrimidin-6-ones, while its reaction with aromatic carbonyl compounds leads to either the same products or Schiff's bases, which can exist in tautomeric equilibrium in solution.
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O. A. Luk'yanov and P. B. Gordeev,Izv. Akad. Nauk, Ser. Khim., 1997, 115 [Russ. Chem. Bull., 1997,46, 110 (Engl. Transl.)].
R. D. Gorak,Farm. Zh. (Kiev), 1988,5, 39 [Ukr. J. Pharm., 1988,5] (in Russian).
E. P. Kyba,Org. Prep. Proceed., 1970,2, 149.
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Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 4, pp. 691–694, April, 1998.
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Luk'yanov, O.A., Gordeev, P.B. Reaction of β-aminopropionohydroxamic acid with aldehydes and ketones. Russ Chem Bull 47, 669–672 (1998). https://doi.org/10.1007/BF02495976
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DOI: https://doi.org/10.1007/BF02495976