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Russian Chemical Bulletin

, Volume 46, Issue 3, pp 539–542 | Cite as

Synthesis of 3-nitropyrid-2(1H)-ones fromC-nitroacetamide and 1,3-dicarbonyl compounds

  • V. P. Kislyi
  • A. M. Shestopalov
  • N. D. Kagramanov
  • V. V. Semenov
Organic Chemistry

Abstract

The reaction of nitroacetamide with 1,3-dicarbonyl compounds afforded 3-nitropyrid-2(1H)-ones. The chemical reactivities of nitroacetamide and nitroacetohydrazide were compared.

Key words

nitroacetamide nitroacetohydrazide 3-nitropyrid-2(1H)-ones 

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References

  1. 1.
    P. S. Moline, Span, ES 512599;Chem. Abstrs., 1984,100, 174671.Google Scholar
  2. 2.
    J. M. Hoffman, J. S. Wai, C. M. Thomas, R. B. Levin, J. A. O'Brien, and M. E. Goldman,J. Med. Chem., 1992,35, 3784.CrossRefGoogle Scholar
  3. 3.
    W. S. Saari, J. S. Wai, T. E. Fisher, C. M. Thomas, J. M. Hoffman, C. Rooney, A. M. Smith, J. H. Jones, D. L. Bamberger, M. E. Goldman, J. A. O'Brien, J. H. Nunberg, J. C. Quintero, W. A. Schleif, E. A. Emini, and P. S. Anderson,J. Med. Chem., 1992,35, 3792.CrossRefGoogle Scholar
  4. 4.
    J. S. Wai, T. Williams, D. L. Bamberger, T. E. Fisher, J. M. Hoffman, R. J. Hudkosky, S. C. MacTough, C. S. Rooney, W. S. Saari, C. M. Thomas, M. E. Goldman, J. A. O'Brien, E. A. Emini, J. H. Nunberg, J. C. Quintero, W. A. Schleif, and P. S. Anderson,J. Med. Chem., 1993,36, 249.CrossRefGoogle Scholar
  5. 5.
    J. M. Hoffman, A. M. Smith, C. S. Rooney, T. E. Fisher, J. S. Wai, C. M. Thomas, D. L. Bamberger, J. L. Barnes, T. M. Wiliams, J. H. Jones, B. D. Olson, J. A. O'Brien, M. E. Goldman, J. H. Nunberg, J. C. Quintero, W. A. Schleif, E. A. Emini, and P. S. Anderson,J. Med. Chem., 1993,36, 953.CrossRefGoogle Scholar
  6. 6.
    S. K. Brownstein,J. Org. Chem., 1958,23, 113.CrossRefGoogle Scholar
  7. 7.
    P. C. Phadke and D. W. Rangnekar,Synthesis., 1986, 860.Google Scholar
  8. 8.
    V. P. Kislyi, A. L. Laikhter, B. I. Ugrak, and V. V. Semenov,Izv. Akad. Nauk, Ser. Khim., 1994, 76 [Russ. Chem. Bull., 1994,43, 70 (Engl. Transl.)].Google Scholar

Copyright information

© Plenum Publishing Corporation 1997

Authors and Affiliations

  • V. P. Kislyi
    • 1
  • A. M. Shestopalov
    • 1
  • N. D. Kagramanov
    • 1
  • V. V. Semenov
    • 1
  1. 1.N. D. Zelinsky Institute of Organic ChemistryRussian Academy of SciencesMoscowRussian Federation

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