Russian Chemical Bulletin

, Volume 46, Issue 3, pp 519–522 | Cite as

Macrocycle opening in crown ethers

3. Transformation of 4′-nitrobenzocrown ethers into podands in the reaction with methylamine
  • S. P. Gromov
  • S. N. Dmitrieva
  • V. E. Krasnovsky
Organic Chemistry


A method for the synthesis of nitrogen-containing podands from 4′-nitrobenzocrown ethers was developed. It involves nucleophilic regioselective cleavage of the macrocycle upon heating with MeNH2.

Key words

4′-nitrobenzocrown ethers macrocycle opening methylamine podands 


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Copyright information

© Plenum Publishing Corporation 1997

Authors and Affiliations

  • S. P. Gromov
    • 1
  • S. N. Dmitrieva
    • 1
  • V. E. Krasnovsky
    • 1
  1. 1.N. N. Semenov Institute of Chemical PhysicsRussian Academy of SciencesMoscowRussian Federation

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