Abstract
C-Phosphorylation of 2-thiazolylformamidines by phosphorus tribromide was studied. It was shown that the 1,3-diazabut-1-enyl (formamidine) substituent can be used as both an activating and protective group. 5-Phosphorylated thiazoles containing either a formamidine fragment or an amino group were obtained. Some properties of the compounds synthesized were studied.
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Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 7, pp. 1353–1359, July, 1999.
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Oshovskii, G.V., Tolmachev, A.A., Yurchenko, A.A. et al. C-PhosphorylatedN 2-2-thiazolylformamidines. Russ Chem Bull 48, 1341–1347 (1999). https://doi.org/10.1007/BF02495301
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DOI: https://doi.org/10.1007/BF02495301