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Chemical approaches to the study of nucleoprotein structures

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Abstract

The main chemical approaches to the study of macromolecular structure and dynamics and to the elucidation of interbiopolymer contact points are considered and illustrated by particular examples. Primary attention is paid to the chemical footprinting and affinity modification methods. The use of bifunctional reagents for the study of nucleoprotein structure architecture is described. The ways of enhancing the selectivity of affinity modification available from the literature are analyzed with an emphasis on catalytically competent (superselective) labeling. The identification of proteins responsible for replication of the tickborne encephalitis virus by this method is described to demonstrate the possibility of the application of the method to multicomponent systems such as the nucleus fraction of infected cells.

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References

  1. V. V. Vlassov, D. Kern, R. Giege, and J. P. Ebel,FEBS Lett., 1981,123, 277.

    Article  CAS  Google Scholar 

  2. T. D. Tulius,TIBS, 1987,12, 297.

    Google Scholar 

  3. H. Heumann, E. Zaychikov, L. Denissova, and T. Hermann,Nucleic Acids and Mol. Biol., 1997,11, 151.

    CAS  Google Scholar 

  4. M. Ishiguro, K. Kimura, A. Yasui, S. Iwata, A. Ueda, and A. Ishihama,J. Mol. Biol., 1988,279, 703.

    Article  Google Scholar 

  5. R. Brimacombe, J. Atmadja, W. Stiege, and D. Schuler,J. Mol. Biol., 1988,199, 115.

    Article  CAS  Google Scholar 

  6. D. G. Knorre and V. V. Vlassov,Affinity Modification of Biopolymers, 1989, CRC Press, Boca Raton, Florida, 269 pp.

    Google Scholar 

  7. T. V. Venkstern, D. M. Graifer, G. G. Karpova, and I. A. Morozov,Biopolimery i Kletka [Biopolymers and Cells], 1990,6, 59 (in Russian).

    Google Scholar 

  8. M. Zenkova, C. Ehresman, J. Cailler, M. Springer, G. Karpova, B. Ehresmann, and P. Romby,Eur. J. Biochem., 1995,231, 726.

    Article  CAS  Google Scholar 

  9. V. N. Ankilova, D. G. Knorre, V. V. Kravchenko, O. I. Lavrik, and G. A. Nevinski,FEBS Lett., 1975,60, 172;FEBS Lett., 1975,60, 172.

    Article  CAS  Google Scholar 

  10. E. D. Sverdlov, S. A. Tsarev, N. N. Modyanov, V. M. Lipkin, M. A. Grachev, E. F. Zaichikov, and A. G. Pletnev,Bioorgan. Khim., 1978,4, 1278 [Sov. J. Bioorg. Chem., 1978,4 (Engl. Transl.)].

    CAS  Google Scholar 

  11. E. D. Sverdlov and S. A. Tsarev,Bioorgan. Khim., 1980,6, 1110 [Sov. J. Bioorg. Chem., 1980,6 (Engl. Transl.)].

    CAS  Google Scholar 

  12. V. G. Budker, A. S. Girshovich, and L. M. Skobel'tsina,Dokl. Akad. Nauk SSSR, 1972,207, 215 [Dokl. Chem. 1972 (Engl. Transl.)].

    CAS  Google Scholar 

  13. E. V. Groman, R. M. Schultz, and L. L. Engel,J. Biol. Chem., 1975,250, 5450.

    CAS  Google Scholar 

  14. M. A. Grachev, A. A. Mustaev, and E. F. Zaychikov, inChemical Modification of Enzymes, 1995, Eds. B. I. Kurganov, N. K. Nagradova, and O. I. Lavrik, Nova Science Publishers, Inc., New York, 309–346.

    Google Scholar 

  15. D. G. Knorre, N. V. Kudrvashova, and O. I. Lavrik,Usp. Khim., 1998,67, 486 [Russ. Chem. Rev., 1998,67 (Engl. Transl.)].

    CAS  Google Scholar 

  16. T. S. Godovikova, M. A. Grachev, I. V. Kutyavin, I. G. Tsarev, V. F. Zarytova, and E. F. Zaychikov,Eur. J. Biochem., 1987,166, 611.

    Article  CAS  Google Scholar 

  17. I. G. Tsarev, A. A. Mustaev, E. F. Zaichikov, T. Yu. Alikina, A. G. Ven'yaminova, and M. N. Repkova,Bioorg. Khim., 1990,16, 765 [Sov. J. Bioorg. Chem., 1990,16 (Engl. Transl.)].

    CAS  Google Scholar 

  18. I. I. Tulokhonov, A. A. Mustaev, and E. F. Zaichikov,Bioorgan. Khim., 1998,24, 422 [Russ. J. Bioorg. Chem., 1998,24 (Engl. Transl.)].

    CAS  Google Scholar 

  19. N. A. Moor, A. Favre, and O. L. Lavrik,FEBS Lett., 1998,427, 1.

    Article  CAS  Google Scholar 

  20. O. V. Morozova, N. A. Belyavskaya, E. F. Zaychikov, E. A. Kvetkova, A. A. Mustaev, and A. G. Pletnev,Biomedical Science, 1991,2, 183.

    CAS  Google Scholar 

  21. O. V. Morozova, I. V. Safronov, V. N. Bahvalova, and M. I. Dobrikov,Bioorg. Med. Chem. Lett., 1998,8, 787.

    Article  CAS  Google Scholar 

  22. M. A. Grachev and A. A. Mustaev,FEBS Lett., 1982,137, 89.

    Article  CAS  Google Scholar 

  23. D. G. Knorre and T. S. Godovikova,FEBS Lett., 1998,433, 9.

    Article  CAS  Google Scholar 

  24. B. R. Braun, B. Bartholomew, G. A. Kassavetis, and E. P. Geiduschek,J. Mol. Biol., 1992,228, 1063.

    Article  CAS  Google Scholar 

  25. J. A. Reems, S. Wood, and S. Mchenry,J. Biol. Chem., 1995,270, 5606.

    Article  CAS  Google Scholar 

  26. T. L. Capson, S. J. Benkovic, and N. G. Nossal,Cell, 1991,65, 249.

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Novosibirsk Institute of Bioorganic Chemistry, Siberian Branch of the Russian Academy of Sciences, 8 prosp. Akad. Lavrent'eva, 630090, Novosibirsk

    D. G. Knorre & T. S. Godovikova

Authors
  1. D. G. Knorre
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  2. T. S. Godovikova
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Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 7, pp. 1225–1231, July, 1999.

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Knorre, D.G., Godovikova, T.S. Chemical approaches to the study of nucleoprotein structures. Russ Chem Bull 48, 1212–1218 (1999). https://doi.org/10.1007/BF02495279

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