Abstract
Enantioselective formation of crystalline 1 : 1 host—guest complexes with (R)-or (S)-1,1,2-triphenylethane-1,2-diol as a host compound allows efficient preparative resolution of (±)-pantolactone. Optically active pantolactones (98%ee) were obtained in 65–67% yield.
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Published inIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 8, pp. 1489–1490, August, 2000.
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Vinogradov, M.G., Kurilov, D.V., Ferapontov, V.A. et al. Efficient resolution of (±)-pantolactone by inclusion crystallization with the use of chiral 1,1,2-triphenylethane-1,2-diol. Russ Chem Bull 49, 1483–1484 (2000). https://doi.org/10.1007/BF02495105
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DOI: https://doi.org/10.1007/BF02495105