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Synthesis of substituted 2-amino-1,3-thiazine-6-thiones

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Abstract

The reaction of thiourea with l-acyl-2-bromoacetylenes in AcOH in the presence of BF3·Et2O affords 2-amino-4-phenyl(2-thienyl)-1,3-thiazine-6-thiones in high yields.

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Published inIzvestiya Akademii Nauk. Seriya Khimicheskaya. No. 11, pp. 1947–1949, November, 2000.

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Glotova, T.E., Komarova, T.N., Nakhmanovich, A.S. et al. Synthesis of substituted 2-amino-1,3-thiazine-6-thiones. Russ Chem Bull 49, 1917–1918 (2000). https://doi.org/10.1007/BF02494937

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  • DOI: https://doi.org/10.1007/BF02494937

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