Summary
The enantiomeric separation of chiral drugs by capillary electrophoresis (CE) in nonaqueous system has been investigated. Successful separation of bepridil, ondansetron and pinacidil in formamide using β-cyclodextrin as chiral selector were achieved. The addition of triethylamine into the background electrolyte enhanced the enantiomeric discrimination.
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Ren, X., Huang, A., Wang, T. et al. Enantiomeric separation of three chiral drugs by nonaqueous capillary electrophoresis with triethylamine as additive. Chromatographia 50, 625–628 (1999). https://doi.org/10.1007/BF02493671
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DOI: https://doi.org/10.1007/BF02493671