Oral Radiology

, Volume 17, Issue 2, pp 11–17 | Cite as

Interstitial brachytherapy for carcinoma of the tongue using microSelectron-HDR

  • Kimishige Shimizutani
  • Yonoshin Koseki
  • Toshihiko Inoue
  • Takehiro Inoue
  • Ken Yoshida
  • Naoya Kakimoto
  • Shumei Murakami
  • Souhei Furukawa
  • Yoshihiro Tanaka
Original Articles

Abstract

Objectives

To analyse the treatment results of high dose rate (HDR) interstitial brachytherapy (ISBT) for early (T1N0, T2N0) mobile tongue cancer using microSelectron-HDR.

Methods

From January 1993 through January 1999, a total of 63 patients with squamous cell carcinomas of the early mobile tongue were treated with microSelectron-HDR (HDR: high dose rate) interstitial brachytherapy at the Department of Radiology, Osaka University Medical School. Tumors were located at the lateral border and ventral surface of the mobile tongue. Nineteen percent of all cases were treated with a combination of prior external radiation and HDR ISBT. Eighty-one percent of all cases were treated with HDR ISBT alone. In the case of HDR ISBT alone, all of which were administered a total dose of 54 Gy/9 fractions/5 days or 60 Gy/10 fractions/8 days. In a combined therapy with an external dose of 30 Gy to 40 Gy, HDR ISBT was given at a total dose of 42–48 Gy.

Results

The local control rate was 84% for HDR IsBT alone and 75% for combined therapy. The difference in the results of HDR ISBT alone and combined therapy was not significant. Nodal metastasis of patients with T1 was 29% (5/17), and that of T2 was 47% (16/34) in the HDR ISBT-alone group and 25% (3/12) in the combined therapy group.

Conclusions

HDR ISBT is useful and easily applied under local anesthesia to early or superficial lesions of the mobile tongue. In addition, this method can eliminate radiation exposure to the medical staff.

Key Words

Brachytherapy Carcinoma of the tongue High dose rate 

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References

  1. 1).
    Yoshida, K., Koizumi, M., Inoue, Ta., Yamazaki, H., Imai, A., Shiomi, H., Yoshioka, Y., Tanaka, E., Shimizutani, K., Furukawa, S., Fuchihata, H. and Inoue, To.: Radiotherapy of early tongue cancer in patients less than 40 years old.Int. J. Radiation Oncology Biol. Phys. 45: 367–371, 1999CrossRefGoogle Scholar
  2. 2).
    Yamazaki, H., Inoue, Ta., Yoshida, K., Imai, A., Yoshioka, Y., Tanaka, E., Shimamoto, S., Nakamura, S., Inoue, To., Nakamura, H., Furukawa, S. and Shimizutani, K.: Influence of age on the results of brachytherapy for early tongue cancer.Int. J. Radiation Oncology Biol. Phys. 49: 931–936, 2001CrossRefGoogle Scholar
  3. 3).
    Inoue, Ta., Inoue, To., Yoshida, K., Yoshioka, Y., Shimamoto, S., Tanaka, E., Yamazaki, H., Shimizutani, K., Teshima, T. and Furukawa, S.: Phase III trial of high-vs low-dose-rate interstitial radiotherapy for early mobile tongue cancer.Int. J. Radiation Oncology Biol. Phys. 51: 171–175, 2001CrossRefGoogle Scholar
  4. 4).
    Spiro, R.H., Alfonso, A.E., Farr, H.W., Strong E.W.: Cervical node metastasis from epidermoid carcinoma of the oral cavity and oropharynx. A critical assessment of current staging.The American Journal of Surgery 128: 562–567, 1974CrossRefGoogle Scholar

Copyright information

© Japanese Society for Oral and Maxillofacial Radiology 2001

Authors and Affiliations

  • Kimishige Shimizutani
    • 1
  • Yonoshin Koseki
    • 1
  • Toshihiko Inoue
    • 2
  • Takehiro Inoue
    • 2
  • Ken Yoshida
    • 2
  • Naoya Kakimoto
    • 3
  • Shumei Murakami
    • 3
  • Souhei Furukawa
    • 3
  • Yoshihiro Tanaka
    • 4
  1. 1.Department of Oral RadiologyOsaka Dental UniversityOsakaJapan
  2. 2.Division of Multidisciplinary RadiotherapyOsaka University Graduate School of MedicineOsakaJapan
  3. 3.Department of Oral & Maxillofacial Radiology, Graduate School of DentistryOsaka UniversityOsakaJapan
  4. 4.Department of DentistryKobe Municipal Chuo HospitalKobeJapan

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