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Femoral component made of Ti-15Mo-5Zr-3Al alloy in total hip arthroplasty

  • Original Articles
  • Published:
Journal of Orthopaedic Science

Abstract

We have developed a femoral component made of Ti-15Mo-5Zr-3Al alloy for total hip prostheses. In vitro mechanical experiments showed that this alloy had better mechanical properties than Ti-6Al-4V alloy with respect to yield strength, tensile strength, elongation, and reduction of area. The elastic modulus of the Ti-15Mo-5Zr-3Al alloy was lower than and its fatigue properties were superior to those of the Ti-6Al-4V alloy. Intraosseous implantation experiments in vivo revealed favorable bone formation around the implants made of Ti-15Mo-5Zr-3Al in rat tibia and no inflammatory responses to the implant. Ti-15Mo-5Zr-3Al alloy appears to be a suitable material for the femoral components of total hip prostheses.

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References

  1. Bobyn JD, Glassman AH, Goto H, et al. The effect of stem stiffness on femoral bone resorption after canine porous-coated total hip arthroplasty. Clin Orthop 1990;261:196–213.

    PubMed  Google Scholar 

  2. Bobyn JD, Mortimer ES, Glassman AH, et al. Producing and avoiding stress shielding: Laboratory and clinical observations of noncemented total hip arthroplasty. Clin Orthop 1992;274:79–96.

    PubMed  Google Scholar 

  3. Charnley J. Arthroplasty of the hip: A new operation. Lancet 1961;1:1129–32.

    Article  PubMed  CAS  Google Scholar 

  4. Cohen MD, Kargacin B, Klein CB, et al. Mechanisms of chromium carcinogenicity and toxicity. Crit Rev Toxicol 1993;23:255–281.

    PubMed  CAS  Google Scholar 

  5. Cook SD, Dalton JE. Biocompatibility and biofunctionality of implanted materials. Alpha Omegan 1992;85:41–7.

    PubMed  CAS  Google Scholar 

  6. Gilani SH, Alibhai Y. Teratogenicity of metals to chick embryos. J Toxicol Environ Health 1990;30:23–31.

    Article  PubMed  CAS  Google Scholar 

  7. Goldring SR, Flannery MS, Petrison KK, et al. Evaluation of connective tissue cell responses to orthopaedic implant materials. Connect Tissue Res 1990;24:77–81.

    Article  PubMed  CAS  Google Scholar 

  8. Huiskes R. Stress shielding and bone resorption in THA: Clinical versus computer-simulated studies. Acta Orthop Belg 1993; 59(suppl. 1):118–29.

    PubMed  Google Scholar 

  9. Léonard A, Lauwerys R. Mutagenicity, carcinogenicity and teratogenicity of cobalt metal and cobalt compounds. Mutat Res 1990;239:17–27.

    PubMed  Google Scholar 

  10. Léonard A, Gerber GB. Mutagenicity, carcinogenicity and teratogenicity of vanadium compounds. Mutat Res 1994;317:81–8.

    PubMed  Google Scholar 

  11. Mertz W. The essential trace elements. Science 1981;213:1332–8.

    PubMed  CAS  Google Scholar 

  12. Nackerdien Z, Kasprzak KS, Rao G, et al. Nickel (II)—and cobalt (II)—dependent damage by hydrogen peroxide to the DNA bases in isolated human chromatin. Cancer Res 1991;51:5837–42.

    PubMed  CAS  Google Scholar 

  13. Nakayama Y, Yamamuro T, Kotoura Y, et al. In vivo measurement of anodic polarization of orthopaedic implant alloys: Comparative studyof in vivo and in vitro experiments. Biomaterials 1989;10:420–4.

    Article  PubMed  CAS  Google Scholar 

  14. Satoh N, Fukuda S, Takizawa M, et al. Chromium-induced carcinoma in the nasal region: A report of four cases. Rhinology 1994;32:47–50.

    PubMed  CAS  Google Scholar 

  15. Takeda S, Kakiushi E, Doi H, et al. Cytotoxicity of pure metals (in Japanese). Shikazairyou Kikai 1989;8:648–52.

    CAS  Google Scholar 

  16. Tsuji E. Inorganic materials. In: Yamamuro T, Oonishi H, editors. Manual of orthopaedic materials (in Japanese). Tokyo: Kanehara 1992:31–9.

    Google Scholar 

  17. Wroblewski BM. Fracture of the stem. In: Wroblewski BM, editor. Revision surgery in total hip arthroplasty. Berlin: Springer, 1990:125–38.

    Google Scholar 

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Authors and Affiliations

  1. Department of Orthopaedic Surgery, Faculty of Medicine, Kyoto University, 54 Kawaharacho Shogoin, Sakyo-ku, 606-01, Kyoto, Japan

    Yasutaka Matsuda, Takashi Nakamura & Kazuhiro Ido

  2. Research Center for Biomedical Engineering, Kyoto University, 54 Kawaharacho Shogoin, Sakyo-ku, 606-01, Kyoto, Japan

    Masanori Oka

  3. Department of Orthopaedic Surgery, School of Medicine, Ehime University, Shizukawa, Onsen-gun, 791-02, Ehime, Japan

    Hideo Okumura

  4. Kobe Steel Ltd., 1 Wakinohamacho, Chuo-ku, 651, Kobe, Japan

    Tomiharu Matsushita

Authors
  1. Yasutaka Matsuda
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  2. Takashi Nakamura
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  3. Kazuhiro Ido
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  4. Masanori Oka
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  5. Hideo Okumura
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  6. Tomiharu Matsushita
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Matsuda, Y., Nakamura, T., Ido, K. et al. Femoral component made of Ti-15Mo-5Zr-3Al alloy in total hip arthroplasty. J Orthop Sci 2, 166–170 (1997). https://doi.org/10.1007/BF02492973

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  • DOI: https://doi.org/10.1007/BF02492973

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