Chromatographia

, Volume 57, Issue 11–12, pp 831–833 | Cite as

Optimization of separation on the basis of unifac parameters and evaluation of the composition of the stationary phase in gas-liquid chromatography

  • N. Q. Mukhamadiev
  • Sh. M. Sayitkulov
  • I. M. Ergashev
  • Kh. F. Khafizov
  • N. I. Fayzullaev
Short Communications Gas Chromatography
  • 41 Downloads

Summary

An algorithm for the optimisation of separation in gas-liquid chromatography based on varying the composition of the stationary phase and the column temperature is presented using the critical parameter Rs≥0.75 (σRs→max). The stationary phase composition, on the basis of retention parameters expressed in terms of vapour pressure and activity coefficient has been derived. Determination of the composition of the stationary liquid was carried out by defining the noture of solute-solvent interactions using group additive value contributions to the activity coefficients. Predicting values on experimentally determined parameters reduced calculation errors by a factor 2 to 3.

The results of the analysis of liquid products from the synthesis of vinyl chloride and chloroprene from acetylene and HCl are presented. The results reveal the mechanism of the reaction and allow optimum conditions to be obtained.

Key Words

Gas chromatography Separation algorithm UNIFAC parameters Stationary phase composition Acetylene, vinyl chloride and chloroprene 

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References

  1. [1]
    Schoenmakers, P.J. Optimization of chromatographic selectivity, Moscow, Mir,1989.Google Scholar
  2. [2]
    Zarkarian, J.A.; Anderson, E.E.; Boyd, J.A.; Prausnitz, J.M.UNIFAC Parameters from gas-liquid Chromatographic data, Ind. Eng. Chem. Process Des. Dev. 1979,18, 4, 657–661.Google Scholar
  3. [3]
    Mukhamadiev, N.Q.; Sayitkulov, Sh.M.; Ergashev, I.M.; Khalilov, K.F.Book of Abstracts of the 222 nd ACS National Meeting, Chicago,2001.Google Scholar
  4. [4]
    Fayzullayev, N.I.; Mukhamadiev, N.Q.; Muradov, K.M.; Ergashev, I.M.All-Russian Conference, “Actual Problems of Analytical Chemistry”, Abstracts of Speeches, Moscow,2002,2, 88–89.Google Scholar

Copyright information

© Friedr. Vieweg & Sohn Verlagsgesellschaft mbH 2003

Authors and Affiliations

  • N. Q. Mukhamadiev
    • 1
  • Sh. M. Sayitkulov
    • 1
  • I. M. Ergashev
    • 1
  • Kh. F. Khafizov
    • 1
  • N. I. Fayzullaev
    • 1
  1. 1.Department of ChemistrySamarkand State UniversitySamarkandUzbekistan

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