Metastatic renal cell carcinoma to head of the pancreas successfully treated by left nephrectomy and pancreatoduodenectomy
We describe a patient with renal cell carcinoma with synchronous metastasis to the head of the pancreas who underwent left nephrectomy and pancreatoduodenectomy. The 57-year-old man was referred to us because of jaundice. Computed tomography of the abdomen showed irregular masses in the left kidney and head of the pancreas. Endoscopic retrograde cholangiopancreatography revealed a filling defect at the head of the pancreas. Renal angiography demonstrated the hypervascular nature of the lesion. No other tumor lesions were discovered. The patient underwent left nephrectomy and pancreatoduodenectomy. Postoperative histopathologic examination revealed clear cell-type renal cell carcinoma in both the renal and pancreatic lesions. At follow-up 3 years later, the patient was alive without evidence of recurrent disease. We present a rare case and assess the role of aggressive surgical management for this unusual problem.
Key wordsmetastatic renal cell carcinoma nephrectomy pancreatoduodenectomy disease-free survival
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- 4.Richie AW, Chisholm GD (1983) The natural history of renal carcinoma. Semin Oncol 10:390–400Google Scholar
- 12.Gohji K, Matsumoto O, Kamidono S (1990) Solitary pancreatic metastasis from renal cell carcinoma. Acta Urol Jpn 36:677–681Google Scholar
- 13.Yanagisawa T, Nakayama K, Kashiwagi M, Tanaka J, Kashiwagi T, Mizuzaki K, Ito A, Akimoto H, Takahashi T, Aoki T, Shimoda T (1993) Three cases of metastatic renal cell carcinoma (in Japanese). Gekashinryo 107:651–656Google Scholar
- 14.Marquand J, Girand B, Mariakas S (1971) Metastase pancreatique revelatice duncancer durein. J Urol Nephrol 77: 595–601Google Scholar
- 15.Tabata T, Kuroda Y, Nishimatsu S (1991) A resected case of renal cell carcinoma to pancreas (in Japanse). Suizo 6:39–44Google Scholar