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Chronic recurrent multifocal osteomyelitis after acute lymphoblastic leukaemia

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Summary

We describe an 8 year old girl who developed chronic recurrent multifocal osteomyelitis (CRMO) in the ilium and clavicle. Treatment for an acute lymphoblastic leukaemia had been finished two months before. After antibiotic therapy, the clinical symptoms improved and no fresh lesions appeared. The aetiology of CRMO is unknown, but we feel that infection may precipitate an immunological reaction.

Résumé

Les auteurs rapportent l'observation d'une fillette de 8 ans, qui présentait une ostéomyélite récurrente chronique multifocale (OCRM), atteignant l'os iliaque et la clavicule. Elle était d'abord soignée pour une leucémie lymphoblastique aiguë dont le traitement était terminé deux mois avant la survenue de l'ORCM. Un traitement antibiotique entraîna l'amélioration clinique sans qu'apparaissent d'autres localisations. L'étiologie de cette maladie est inconnue, mais nous estimons comme probable qu'une infection soit la cause d'une réaction immunologique.

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Authors and Affiliations

  1. Department of Orthopaedics, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain

    J. C. Abril, F. Castillo & A. F. Loewinsonh

  2. Department of Pathology, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain

    C. Rivas

  3. Department of Paediatrics, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain

    M. Bernacer

Authors
  1. J. C. Abril
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  2. F. Castillo
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  3. A. F. Loewinsonh
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  4. C. Rivas
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  5. M. Bernacer
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Abril, J.C., Castillo, F., Loewinsonh, A.F. et al. Chronic recurrent multifocal osteomyelitis after acute lymphoblastic leukaemia. International Orthopaedics 18, 126–128 (1994). https://doi.org/10.1007/BF02484425

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  • DOI: https://doi.org/10.1007/BF02484425

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