Skip to main content

Advertisement

Log in

Treatment for accidental occlusion of the hepatic artery after hepatic resection: Report of two cases

  • Case Reports
  • Published:
Surgery Today Aims and scope Submit manuscript

Abstract

Two patients in whom accidental hepatic artery occlusion (HAO) occurred after hepatic resection (Hx) were reported. A 59-year-old female who underwent Hx for hepatocellular carcinoma with underlying liver cirrhosis developed HAO on postoperative day (POD) 14 and died of hepatic failure on POD 23. The autopsy findings showed multiple necrosis in the remnant liver and an extraluminal hematoma of the hepatic artery, suggesting an injury caused by Pringle’s maneuver. The second case was a 53-year-old male who underwent Hx for cholangiocarcinoma without any underlying liver disease. He developed HAO on POD 6, and radiological studies indicated a pseudoaneurysma formation and severe stenosis of the hepatic artery. It was speculated that the cause of the HAO was intraluminal injury of the hepatic artery during an angiographic study conducted prior to Hx. Partial arterialization of the portal vein was performed, following which his liver function test results improved. In both cases, measuring the serum hepatocyte growth factor level and the hepatic vein oxygen saturation proved useful, not only for determining the degree of liver injury, but also for predicting the outcome after treatments for HAO. Furthermore, the partial arterialization of the portal vein for HAO after Hx may rescue the normal remnant liver.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Reuter SR, Palmaz JC, Berk RN (1980) Hepatic artery injury during portacaval shunt surgery. Am J Roentgenol 134:349–353

    CAS  Google Scholar 

  2. Halasz NA (1991) Cholecystectomy and hepatic artery injuries. Arch Surg 126:137–138

    CAS  PubMed  Google Scholar 

  3. Someda H, Moriyasu F, Fujimoto M, Hamato N, Nabeshima M, Nishikawa K, Okuma M, Tanaka K, Ozawa K (1995) Vascular complications in living related liver transplantation detected with intraoperative and postoperative Doppler US. J Hepatol 22:623–632

    Article  CAS  PubMed  Google Scholar 

  4. Holbert BL, Baron RL, Dodd GD (1996) Hepatic infarction caused by arterial insufficiency: spectrum and evolution of CT findings. Am J Roentgenol 166:815–820

    CAS  Google Scholar 

  5. Siablis D, Tepetes K, Vasiou K, Karnabatidis D, Perifanos S, Tzorakoleftherakis E (1996) Hepatic artery pseudoaneurysm following laparoscopic cholecystectomy, transcatheter intraarterial embolization. Hepatogastroenterology 43:1343–1346

    CAS  PubMed  Google Scholar 

  6. Graham DD, May AK, Moore M, Young JS (1997) Management of hepatic artery injury, case report. Am Surg 63:327–329

    CAS  PubMed  Google Scholar 

  7. Orons PD, Zajko AB, Bron KM, Trecha GT, Selby RR, Fung JJ (1995) Hepatic artery angioplasty after liver transplantation, experience in 21 allografts. J Vasc Interv Radiol 6:523–529

    Article  CAS  PubMed  Google Scholar 

  8. Ueno S (1994) An experimental study on the correlation between hepatic hemodynamics and ultrastructural and immunohistochemical changes in sinusoidal endothelial cells after major hepatectomy (in Japanese with English abstract). Nippon Geka Gakkai Zasshi (J Jpn Surg Soc) 95:248–258

    CAS  PubMed  Google Scholar 

  9. Nonami T, Asahi K, Harada A, Nakao A, Takagi H (1991) Effect of hyperdynamic circulatory support on hepatic hemodynamics, oxygen supply and demand after massive hepatectomy. Surgery 109:277–283

    CAS  PubMed  Google Scholar 

  10. Nakamura T, Nishizawa T, Hagiya M, Seki T, Shimonishi M, Sugimura A, Tashiro K, Shimizu S (1989) Molecular cloning and expression of human hepatocyte growth factor. Nature 342:440–443

    Article  CAS  PubMed  Google Scholar 

  11. Gohda E, Tsubouchi H, Nakayama H, Hirono S, Sakiyama O, Takahashi K, Miyazaki H, Hashimoto S, Daikuhara Y (1988) Purification and partial characterization of hepatocyte growth factor from plasma of a patient with fulminant hepatic failure. J Clin Invest 81:414–419

    Article  CAS  PubMed  Google Scholar 

  12. Tsubouchi H, Kawakami S, Hirono S, Miyazaki H, Kimoto M, Arima T, Sekiyama K, Yoshiba M, Arakaki N, Daikuhara Y (1992) Prediction of outcome in fulminant hepatic failure by serum human hepatocyte growth factor. Lancet 340:307

    Article  CAS  PubMed  Google Scholar 

  13. Nitta N, Yamamoto S, Ozaki N, Morimoto T, Mori K, Yamaoka Y, Ozawa K (1988) Is the deterioration of liver viability due to hepatic warm ischemia or reinflow of pooled-portal blood in intermittent portal triad cross-clamping? Res Exp Med Berl 188:341–350

    Article  CAS  PubMed  Google Scholar 

  14. Ueno S, Tanabe G, Kawaida K, Hamanoue M, Mitsue S, Ogura Y, Yoshidome S, Nuruki K, Aikou T (1997) Serum hepatocyte growth factor (HGF) levels predict the outcomes in hepatectomized patients with postoperative hyperbilirubinemia. Int Hepatol Commun 6:294–299

    Article  Google Scholar 

  15. Meier HA, Hannemann L, Specht M, Schaffartzik W, Spies C, Reinhart K (1994) The relationship between mixed venous and hepatic venous O2 saturation in patients with septic shock. Adv Exp Med Biol 345:701–707

    Google Scholar 

  16. Takahashi T, Kunimoto F, Ichikawa H, Ishikawa S, Sato Y, Hasegawa Y, Morishita Y (1996) Gastric intramucosal pH and hepatic venous oximetry after cardiopulmonary bypass in valve replacement patients. Cardiovasc Surg 4:308–310

    Article  CAS  PubMed  Google Scholar 

  17. Shimizu H, Miyazaki M, Ito H, Nakagawa K, Ambiru S, Nakajima N (1996) Evaluation of early graft function by hepatic venous hemoglobin oxygen saturation following orthotopic liver transplantation in the rat. Transplantation 62:1499–1501

    Article  CAS  PubMed  Google Scholar 

  18. Kainuma M, Fujiwara Y, Kimura N, Shitaokoshi A, Nakashima K, Shimada Y (1991) Monitoring hepatic venous hemoglobin oxygen saturation in patients undergoing liver surgery. Anesthesiology 74:49–52

    Article  CAS  PubMed  Google Scholar 

  19. Kainuma M, Nakashima K, Sakuma I, Kawase M, Komatsu T, Shimada Y, Nimura Y, Nonami T (1992) Hepatic venous hemoglobin oxygen saturation predicts liver dysfunction after hepatectomy. Anesthesiology 76:379–386

    Article  CAS  PubMed  Google Scholar 

  20. Ueno S, Kobayashi Y, Kurita K, Tanabe G, Aikou T (1995) Effect of prior portosystemic shunt on early hepatic hemodynamics and sinusoids following 84% hepatectomy in dogs. Res Exp Med 195:1–8

    Article  CAS  Google Scholar 

  21. Aldrete JS, Soyer MT, Han SY (1981) Long term effects of arterialization of the portal vein stump in dogs with Eck’s fistula. Br J Surg 68:656–660

    Article  CAS  PubMed  Google Scholar 

  22. Saric J, Faugon H, Beliard R, Perissat J, Balabaud C, Dubuisson L, Bioulac P (1981) Liver arterialization improves hepatocytes ultrastructure in rats with portacaval shunts. Dig Dis Sci 26:225–231

    Article  CAS  PubMed  Google Scholar 

  23. Otte JB, Reynaert M, De Hemptinne B, Geubel A, Carlier M, Jamart J, Lambotte L, Kestens PJ (1982) Arterialization of the portal vein in conjunction with a therapeutic portacaval shunt, hemodynamic investigations and results in 75 patients. Ann Surg 196:656–663

    Article  CAS  PubMed  Google Scholar 

  24. Iseki J, Touyama K, Noie T, Nakagami K, Takagi M, Hakamada K, Tanaka A, Yamada A, Hanakita J, Suwa H (1992) Partial portal arterialization for the prevention of massive liver necrosis following extended pancreatobiliary surgery, experience of two cases. Surg Today 22:568–571

    Article  CAS  PubMed  Google Scholar 

  25. Morimoto T, Terasaki M, Higashiyama H, Tanaka K, Uemoto S, Tanaka A, Shimahara Y, Mori K, Kim HJ, Kamiyama Y (1992) Clinical application of arterialization of portal vein in living related donor partial liver transplantation. Transplant Int 5:151–154

    CAS  Google Scholar 

  26. Erhard J, Lange R, Giebler R, Rauen U, de Groot H, Eigler FW (1995) Arterialization of the portal vein in orthotopic and auxiliary liver transplantation; a report of three cases. Transplantation 60:877–879

    CAS  PubMed  Google Scholar 

  27. Neelamekam TK, Geoghegan JG, Curry M, Hegarty JE, Traynor O, McEntee GP (1997) Delayed correction of portal hypertension after portal vein conduit arterialization in liver transplantation. Transplantation 63:1029–1030

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Tanabe, G., Kawaida, K., Hamanoue, M. et al. Treatment for accidental occlusion of the hepatic artery after hepatic resection: Report of two cases. Surg Today 29, 268–272 (1999). https://doi.org/10.1007/BF02483020

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02483020

Key Words

Navigation