Abstract
A 70-year-old woman presented with mild left hemiparesis and intermittent global headache. Magnetic resonance imaging showed a 6×6×6-cm tumor in the right frontal lobe, and abdominal computed tomography revealed a 8×8×7-cm mass lesion in the left kidney. Magnetic resonance imaging showed that the brain tumor consisted of a central hyperintense cystic component and an outer hypointense component. The patient underwent total surgical excision of the intracranial mass. Histological and immunohistochemical examination showed that the lesion was a lipomatous meningioma harboring metastatic renal-cell carcinoma. Both of these tumors are rare. The magnetic resonance imaging findings are indicative of but not specific to meningioma harboring metastatic tumor.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Tally PW, Laws ER Jr, Scheithauer BW (1998) Metastases of central nervous system neoplasms: case report. J Neurosurg 68:811–816
Schmitt HP (1984) Metastasis of malignant neoplasms to intracranial tumours: the “tumour-in-a-tumour” phenomenon. Virchows Arch A Pathol Anat Histopathol 405:155–160
Lodrini S, Savoiardo M (1981) Metastasis of carcinoma to intracranial meningioma. Report of two cases and review of the literature. Cancer 48:2668–2673
Smith TW, Wang SY, Schoene WC (1981) Malignant carcinoid tumor metastatic to a meningioma. Cancer 47:1872–1877
Honma K, Hara K, Sawai T (1989) Tumour-to-tumor metastasis: a report of two unusual autopsy cases. Virchows Arch A Pathol Anat Histopathol 416:153–157
Wong A, Koszyca B, Blumbergs PC, et al. (1999) Malignant melanoma metastatic to a meningioma. Pathology 31:162–165
Osterberg DH (1957) Metastases of carcinoma to meningioma. J Neurosurg 14:337–343
Watanabe T, Fujisawa H, Hasegawa M, et al (2002) Metastasis of breast cancer to intracranial meningioma. Case report. Am J Clin Oncol 25:414–417
Bhargava P, McGrail KM, Mans HJ, et al (1999) Lung carcinoma presenting as metastasis to intracranial meningioma. Case report and review of literature. Am J Clin Oncol 22:199–202
Stortbecker TP (1951) Metastatic hypernephroma of the brain from a neurosurgical point of view. J Neurosurg 8:185–197
Breadmore R, House R, Gonzales M (1994) Metastasis of renal cell carcinoma to a meningioma. Australas Radiol 38:141–143
Han HS, Kim EY, Han JY, et al (2000) Metastatic renal cell carcinoma in a meningioma: a case report. J Korean Med Sci 15:593–597
Roncaroli F, Scheithauer BW, Laeng RH, et al (2001) Lipomatous meningioma: a clinicopathologic study of 18 cases with special reference to the issue of metaplasia. Am J Surg Pathol 25:769–775
Bailey P, Bucy PC (1931) The origin and nature of meningeal tumors. Am J Cancer 15:15–54
Kleihues P, Burger PC, Scheithauer BW (1993) The new WHO classification of brain tumors. Brain Pathol 3:255–268
Louis DN, Scheithauer BW, Budka H, et al (2000) Meningiomas In: Kleihues P, Canevee WK (eds) World Health Organization classification of tumours: tumours of the central nervous system. IARC, Lyon, pp 176–184
Chambers PW, Davis RL, Blanding JD, et al (1980) Metastases to primary intracranial meningiomas and neurilemomas. Arch Pathol Lab Med 104:350–354
Ogawa H, Iwaya K, Izumi M, et al (2002) Expression of CD 10 by stromal cells during colorectal tumor development. Hum Pathol 33:806–811
Suzuki T, Ino K, Kikkawa F, et al (2002) Neutral endopeptidase/ CD10 expression during phorbol ester-induced differentiation of choriocarcinoma cells through the protein kinase C-and extracellular signal-regulated kinase-dependent signalling pathway. Placenta 23:475–482
Kanitakis J, Bourchany D, Claudy A (2000) Expression of the CD10 antigen (neutral endopeptidase) by mesenchymal tumors of the skin. Anticancer Res 20:3539–3544
Kim MK, Kim S (2002) Immunohistochemical profile of common epithelial neoplasms arising in the kidney. Appl Immunohistochem Mol Morphol 10:332–338
Yang B, Ali SZ, Rosenthal DL (2002) CD10 facilitates the diagnosis of metastatic renal cell carcinoma from primary adrenal cortical neoplasm in adrenal fine-needle aspiration. Diagn Cytopathol 27:149–152
Chu P, Arber DA (2000) Paraffin-section detection of CD10 in 505 nonhematopoietic neoplasms. Frequent expression in renal cell carcinoma and endometrial stromal sarcoma. Am J Clin Pathol 113:374–382
Avery AK, Beckstead J, Renshaw AA, et al (2000) Use of antibodies to RCC and CD10 in the differential diagnosis of renal neoplasms. Am J Surg Pathol 24:203–210
Savoiardo M, Lodrini S (1980) Hypodense area within a meningioma: metastasis from breast cancer. Neuroradiology 20:107–110
Rohringer M, Sutherland GR, Louw DF, et al (1989) Incidence and clinicopathologic features of meningioma. J Neurosurg 71:665–672
Uchino A, Hasuo K, Mizushima A, et al (1996) Intracranial metastasis of renal cell carcinoma: MR imaging. Radiat Med 14:71–76
Kono K, Inoue Y, Nakayama K, et al (2001) The role of diffusion-weighted imaging in patients with brain tumors. AJNR Am J Neuroradiol 22:1081–1088
Filippi CG, Edgar MA, Ulug AM, et al (2001) Appearance of meningiomas on diffusion-weighted images: correlating diffusion constants with histopathologic findings. AJNR Am J Neuroradiol 22:65–72
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Kimiwada, T., Motohashi, O., Kumabe, T. et al. Lipomatous meningioma of the brain harboring metastatic renal-cell carcinoma: A case report. Brain Tumor Pathol 21, 47–52 (2004). https://doi.org/10.1007/BF02482177
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02482177