Abstract
We explore the association between the site of attachment of nonfamilial left atrial myxoma and it’s recurrence. Forty-three (11 male and 32 female; mean age, 55.9±13.6 years) of 49 consecutive patients with nonfamilial left atrial myxoma who had been evaluated with preoperative echocardiography, X were available for postoperative follow-up with transthoracic echocardiography, transesophageal echocardiography, or both, for an average period of 85.2±54.2 months (range, 6.5 to 215.5 months). We compared preoperative clinical and echocardiographic features of recurrent and nonrecurrent myxomas. Three (7%) of the 43 cases of atrial myxoma recurred at the same site after 24.1±7.6 months. Involvement of the mitral valve annulus or mitral valve leaflet (3 vs 0,p<0.001) was observed in the recurrent myxomas, but the two groups did not differ significantly in any other clinical features, laboratory data, or echocardiographic features of the recurrent and nonrecurrent myxoma. Preoperative echocardiographic observation of involvement of the mitral valve annulus or mitral valve leaflet may predict recurrence after surgery. Regular follow-up echocardiography was useful in the early detection of recurrence.
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Reynen K: Frequency of primary tumors of the heart. Am J cardiol 1996;77: 107.
MacGowan SW, Sidhu P, Aherne T, et al: Atrial myxoma: national incidence, diagnosis and surgical management. Ir J Med Sci 1993;162: 23–226.
Salcedo EE, Cohen GI, White RD, et al: Cardiac tumors: diagnosis and treatment. Curr Probl Cardiol 1992;17: 73.
Hanson EC: Cardiac tumors: a current perspective. NY state J Med 1992;92: 41.
Bjessmo S, Ivert T: Cardiac myxoma: 40 years’ experience in 63 patients. Ann Thorac Surg 1997;63: 697–700.
Goswami KC, Shrivastava S, Bahl VK, et al: Cardiac myxomas: clinical and echocardiographic profile. Intl J Cardiol 1998;63: 251–259.
Dato GMA, Benedictis MD, Dato A, et al: Long term follow up of cardiac myxomas. J Cardiovasc Surg 1993;34: 141–143.
Castells E, Ferran Y, Octavi de Toledo MC, et al: Cardiac myxomas: surgical treatment, long term results and recurrence. J Cardiovasc Surg 1993;34: 49–53.
Bastos P, Barreiros F, Casanova J, et al: Cardiac myxomas: surgical treatment and long term results. Cardiovasc Surg 1995;3: 595–597.
McCarthyy PM, Piehler JM, Schaff HV, et al: The significance of multiple, recurrent and “complex” cardiac myxomas. Thorac Cardiovasc Surg 1986;91: 389–396.
Fyke II FE, Seward JB, Edwards WD, et al: Primary cardiac tumors: experience with 30 consecutive patients since the introduction of two-dimensional echocardiography. J Am Coll Cardiol 1985;5: 1465–1473.
Oh JK, Seward JB, Tajik AJ: Cardiac tumors and masses. In: Oh JK, Seward JB, Tajik AJ: The Echo Manual. 2nd ed. Philadelphia, Penn, Mayo Foundation; 1999: 205–214.
Reynen K: Cardiac myxomas. N Engl J Med 1995;33: 1610–1617.
Markel ML, Waller BF, Armstrong WF: Cardiac myxoma: a review. Medicine 1987;66(2): 114–125.
Brown AS, Why H, Monaghan MJ: Value of multiplane transesophageal echocardiography in recurrent atrial myxoma. Br Heart J 1994;71(6): 540.
Hanson EC, Gill CC, Razavi M, et al: The Surgical treatment of atrial myxoma: clinical experience and late results in 33 patients. J Thorac Cardiovasc Surg 1989;89: 298–303.
Waller DA, Ettles DF, Saunders NR, et al: Recurrent myxoma: the surgical implications of two distinct groups of patients. Thorac Cardiovasc Surgeon 1989;37: 226–230.
Alkhulaifi AM, Horner S, Pugsley WB, et al: Recurrent left atrial myxoma. Cardiovasc Surg 1994;2: 232–236.
Gray IR, Williams WG: Recurring cardiac myxoma. Br Heart J 1985;53: 645–649.
Shinfeld A, Katsumata T, Westaby S: Recurrent cardiac myxoma: seeding or multifocal disease? Ann Thorac Surg 1998;66: 285–288.
Farah MG: Familial cardiac myxoma: a study of relatives of patients with myxoma. Chest 1994;105: 65–68.
Bhan A, Mehrotra R, Choudhary SK, et al: Surgical experience with intracardiac myxoma: long term follow up. Ann Thorac Surg 1998;66: 810–813.
Attar S, Lee YC, Singleton R, et al: Cardiac myxoma. Ann Thorac Surg 1980;29: 397–405.
Richardson JV, Brandt B III, Doty DB, et al: Surgical treatment of atrial myxomas: early and late results of 11 operations and review of the literature. Ann Thorac Surg 1979;28: 354–358.
Centofanti P, Rosa ED, Deorsola L et al: Primary cardiac tumors: Early and late results of surgical treatment in 91 patients. Ann Thorac Surg 1999;68: 1236–1241.
Sellke FW, Lemmer JH Jr, Vandenberg BF, et al: Surgical treatment of cardiac myxomas: long-term results. Ann Thorac Surg 1990;50: 557–561.
Kabbani SS, Jokhadar M, Meada R et al: Atrial myxoma: Report of 24 operations using the biatrial approach. Ann Thorac Surg 1994;58: 483–484.
Read RC, White HJ, Murphy ML, et al: The malignant potentiality of left atrial myxoma. J Thorc Cardiovasc Surg 1974;68: 857–868.
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Shrestha, B., Ishizuka, N., Tanimoto, K. et al. Echocardiographically evaluated site of attachment of atrial myxoma may predict recurrence. J Med Ultrasonics 30, 69–75 (2003). https://doi.org/10.1007/BF02481366
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DOI: https://doi.org/10.1007/BF02481366