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Brain Tumor Pathology

, Volume 14, Issue 1, pp 71–74 | Cite as

Long-term survival in a young patient with anaplastic glioma

  • Hirofumi Naganuma
  • Atsushi Sasaki
  • Eiji Satoh
  • Mitsuyasu Nagasaka
  • Shiro Isoe
  • Shin Nakano
  • Hideaki Nukui
Case Report

Abstract

A 26-year-old man with anaplastic glioma in the left frontoparietal lobe survived for 9 years and 9 months after combined therapy, including subtotal resection, postoperative irradiation, and chemotherapy. The tumor recurred and he received immunotherapy using lymphokine-activated killer (LAK) cells. At the last LAK cell infusion, infection of the Ommaya reservoir occurred, but subsided after antibiotics were administered. Follow-up neuroimaging showed no recurrence of the tumor. Review of the surgical specimens found that the original diagnosis of glioblastoma was inconclusive, although the tumor is considered to be a type of anaplastic glioma.

Key words

Glioblastoma Anaplastic glioma Long-term survival Immunotherapy 

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Copyright information

© The Japan Society of Brain Tumor Pathology 1997

Authors and Affiliations

  • Hirofumi Naganuma
    • 1
  • Atsushi Sasaki
    • 1
  • Eiji Satoh
    • 1
  • Mitsuyasu Nagasaka
    • 1
  • Shiro Isoe
    • 1
  • Shin Nakano
    • 1
  • Hideaki Nukui
    • 1
  1. 1.Department of NeurosurgeryYamanashi Medical UniversityYamanashiJapan

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