The bulletin of mathematical biophysics

, Volume 7, Issue 3, pp 151–160 | Cite as

A reinterpretation of the mathematical biophysics of the central nervous system in the light of neurophysiological findings

  • N. Rashevsky


The fundamental equations for the interaction between neurons used in mathematical biophysics seem at first incompatible with the actual neurophysiological findings on the synaptic transmission. It is shown, however, that those equations may be readily interpreted in terms of accepted neurophysiological views. What has been termed “synapse” in mathematical biophysics must be regarded as a complicated network of internuncial neurons. It is shown that, under rather conditions, the number of those interneurons willstatistically vary with time according to the differential equation postulated for the excitatory and inhibitory factors. The latter are thus interpreted as the number of excitatory and inhibitory interneurons.


Synaptic Transmission Inhibitory Interneuron Closed Circuit Mathematical Biophysics Synaptic Delay 
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Copyright information

© The University of Chicago Press 1945

Authors and Affiliations

  • N. Rashevsky
    • 1
  1. 1.The University of ChicagoChicagoUSA

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