The bulletin of mathematical biophysics

, Volume 13, Issue 4, pp 263–271 | Cite as

Determination of the sensitive volume by irradiation and the ionization density

  • I. Opatowski


Lea's formula for the determination of size of the sensitive volume is corrected and applied to experiments on inactivation of the tobacco mosaic virus using three different wave lengths of x-rays. The purely geometric concept of the sensitive volume is not sufficient for explaining the known dependence of the inactivation of this virus on wave length. The concept of transfer of energy around the ionizing particles is discussed in this connection in a manner similar to that suggested by Pollard and Forro for the inactivation of theT−1 phage, and results similar to those given by these authors are obtained from an analysis of the inactivation data of J. W. Gowen (tobacco mosaic virus). Differences of interpretation of these two sets of experiments carried out with different types of radiation are pointed out.


Wave Length Tobacco Mosaic Virus Ionization Density Average Energy Sensitive Volume 
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Copyright information

© The University of Chicago Press 1951

Authors and Affiliations

  • I. Opatowski
    • 1
  1. 1.Communittee on Mathematical BiologyThe University of ChicagoChicagoUSA

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