The bulletin of mathematical biophysics

, Volume 23, Issue 2, pp 159–163 | Cite as

A model for conditioning and the effect of spaced trials in learning

  • H. D. Landahl


A mechanism is suggested in which a postulated substance can enter a synaptic region only during the simultaneous action of a conditioned and an unconditioned stimulus. If this substance remains and produces a physico-chemical change, then a consequence is that the degree of learning will depend on the spacing of conditioning trials and the time constant of the process will be related to the rate of diffusion or transport of the substance along the axon.


Nicotine Unconditioned Stimulus Biophysics Volume Synaptic Connection Permanent Change 
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Copyright information

© University of Chicago 1961

Authors and Affiliations

  • H. D. Landahl
    • 1
  1. 1.Committee on Mathematical BiologyThe University of ChicagoChicagoUSA

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