The bulletin of mathematical biophysics

, Volume 12, Issue 1, pp 57–83 | Cite as

The steady state kinetics of some biological systems: III. Thermodynamic aspects

  • John Z. Hearon


Some thermodynamic aspects of steady systems are considered. The time rates of changes, “flux”, of various thermodynamic quantities are formulated. In particular the free energy flux in the steady state, the difference between the free energy flux in the steady and time dependent states and the change in free energy flux upon transition between steady states are discussed. Equations are derived which exhibit the formal similarities and differences between the free energy flux and the conventional free energy change. The temperature dependence of the steady state rate is examined and conditions for “mastery” by a single step discussed. A brief discussion of the role ofrate in the coupling of exergonic and endergonic reactions is given.


Free Energy Steady State Rate Steady State Kinetic Concentration Term Hamiltonian Principle 
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Copyright information

© The University of Chicago Press 1950

Authors and Affiliations

  • John Z. Hearon
    • 1
  1. 1.Committee on Mathematical BiologyThe University of ChicagoChicagoUSA

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