Summary
A device that provides a versatile and easily controllable means of producing transient current waveforms for the selective inactivation of nerve-fibre groups is described. It is constructed from readily available components, such as integrated circuits and optically coupled isolators. Good separation between A-fibre and C-fibre responses in the rat saphenous nerve has been achieved.
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References
Alpsan, D., Eccles, M. J., Lal, S. andWormald, D. I. (1973) A device for selectively blocking nerve fibres using a transient polarising current.J. Physiol. 232, 9–10.
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Zimmerman, M. (1968) Selective activation of C fibres.Pflügers Arch. Ges. Physiol. 301, 329–339.
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Alpsan, D., Wormald, D.I., Lal, S. et al. A system for selectively inactivating nerve fibres by a polarising, transient current. Med. & biol. Engng. 14, 90–93 (1976). https://doi.org/10.1007/BF02477098
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DOI: https://doi.org/10.1007/BF02477098