The bulletin of mathematical biophysics

, Volume 27, Issue 4, pp 431–434 | Cite as

The use of two radiotracers for transfer-rate determinations in closed two compartment systems

  • Felix Leitner


The sensitivity and “specificity” of measurements for the determination of transferates are enhanced by the use of an additional radiotracer, serving to trace the unlabelled substance. This method presents advantages mostly in systems outside their steady state but only exeptionally in steady state systems.


Biophysics Volume Compartment System Chemical Assay Sssa Total Substance 
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  1. Robertson, J. S. 1957. “Theory and Use of Tracers in Determining Transfer Rates in Biological Systems.”Physiol. Rev.,37, 133–154.Google Scholar
  2. Sheppard, C. W. 1962.Basic Principles of the Tracer Method. New York: John Wiley & Sons, Inc.Google Scholar

Copyright information

© N. Rashevsky 1965

Authors and Affiliations

  • Felix Leitner
    • 1
  1. 1.Department of MicrobiologyMichael Reese Hosptial and Medical CenterChicago

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