The bulletin of mathematical biophysics

, Volume 33, Issue 3, pp 303–319 | Cite as

Some realizations of (M, R)-systems and their interpretation

  • Robert Rosen


Some years ago (Rosen 1958a, b; 1959) we described a class of metaphorical, relational paradigms for cellular activity which we termed (M, R)-systems. A sizable amount of subsequent work, to be itemized below, has been devoted to an exploration of some of the properties of these systems. The main purpose of the present paper is to put this class of paradigms into a general system-theoretic perspective, with a particular view to appraising the relation between the type of system description embodied in the (M, R)-system and other kinds of physical and mathematical descriptions of cellular systems. Thus, the principal aim is to establish the relationships and connections between the global relational formalism embodied in the (M, R)-systems and the empirical descriptions which still represent the bulk of our biological knowledge.


Rosen System Description Sequential Machine Oriented Graph Dynamical Description 
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Copyright information

© N. Rashevsky 1968

Authors and Affiliations

  • Robert Rosen
    • 1
  1. 1.Center for Theoretical BiologyState University of New York at BuffaloUSA

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