The bulletin of mathematical biophysics

, Volume 33, Issue 4, pp 589–594 | Cite as

A quantum model for controlled enzymic reactions: II. Controlled biochemical networks

  • S. Comorosan
  • P. Murgoci


Two control units, the switching and the two factor discriminating net are described. They are derived as a consequence of the enzymic oscillatory behavior induced by substrate “perturbation”.

A complex network encompassing long sequences of metabolic reactions is constructed and the organization of cellular metabolic activities in well defined “regimes” and “states” inferred.


Biochemical Network Switching Type Cellular Metabolic Activity Hexo Energy Generate System 
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  1. Comorosan, S. and P. Murgoci. 1969. “A Quantum-Theoretic Approach to Enzyme Specificity. Proposals for a new Type of Biochemical Control Mechanism.”Bull. Math. Biophysics,31, 623–635.MATHCrossRefGoogle Scholar
  2. —— and ——. 1970. “A Quantum Model for Controlled Enzymic Reactions.” —Ibid.,33, 343–386.Google Scholar
  3. —— 1970. “Control of Cellular Reactions Through a New Mechanism: The Biochemical Flip-Flop.”Nature (London),227, 1243–1246.CrossRefGoogle Scholar

Copyright information

© N. Rashevsky 1968

Authors and Affiliations

  • S. Comorosan
    • 1
  • P. Murgoci
    • 1
  1. 1.Postgraduate Department of BiochemistryFundeni HospitalBucharestRomania

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