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Accelerated hydrolysis of esters catalyzed by receptors, II. Degradation of RNA by polyvinylpyrrolidone

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Abstract

The nonenzymatic hydrolysis of RNA by polyvinylpyrrolidone (PVP) has been investigated. A bell-shaped kinetics was observed when the first order rate constant of the reaction was ploted as a function of PVP concentration, which means the kinetic feature of PVP as a degradative receptor distinct from those of degradative enzymes (e.g., ribonuclease).

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Authors and Affiliations

  1. Department of Biochemistry, Chungnam National University, 305-764, Taejon, Republic of Korea

    Sung-Sik You, Hyeong-Won Ryu, Young Cho & Thong-Sung Ko

  2. Department of Chemistry, Soonchunhyang University, Asan 336-745, Chungnam, Republic of Korea

    Dae-Young Kim

Authors
  1. Sung-Sik You
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  2. Hyeong-Won Ryu
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  3. Young Cho
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  4. Dae-Young Kim
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  5. Thong-Sung Ko
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You, SS., Ryu, HW., Cho, Y. et al. Accelerated hydrolysis of esters catalyzed by receptors, II. Degradation of RNA by polyvinylpyrrolidone. React Kinet Catal Lett 66, 121–126 (1999). https://doi.org/10.1007/BF02475750

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  • DOI: https://doi.org/10.1007/BF02475750

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