Reaction Kinetics and Catalysis Letters

, Volume 68, Issue 1, pp 105–113 | Cite as

Quantification of the formation of free radicals in macrophage systems

  • Dezső Gál
  • András Németh
  • Tamás Kriska


A mechanism is suggested for the zymosan stimulated, luminol dependent chemiluminescence of macrophage system both in the absence and in the presence of free radical inhibitor. Based on the mechanism and relevant data of elementary rate constants computer simulation has been performed in order to describe the free radical formation and consumption, the kinetics of the chemiluminescence signal as well as the consumption of the inhibitor and luminol molecules in the course of the overall process.


Chemiluminescence macrophage system oxidation of luminol inhibition of luminol dependent chemiluminescence 


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Copyright information

© Akadémiai Kiadó 1999

Authors and Affiliations

  • Dezső Gál
    • 1
  • András Németh
    • 1
  • Tamás Kriska
    • 1
  1. 1.Institute of Chemistry, Chemical Research CenterHungarian Academy of SciencesBudapestHungary

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