Skip to main content
Log in

Clear cell carcinoma of the thyroid. A case report

  • Case Reports
  • Published:
The Japanese journal of surgery Aims and scope Submit manuscript

Abstract

A rare case of clear cell carcinoma of the thyroid is presented herein. A 31-year-old male had a large soft tumor in the right lobe of the thyroid which showed a hot nodule on scintigram with99mTc. A right hemithyroidectomy was thus performed after the preoperative diagnosis of a functioning tumor had been made. At surgery, a tiny nodule behind the tumor was found and the histopathological diagnoses of the large tumor and the tiny nodule were clear cell carcinoma and papillary carcinoma, respectively. The thyroglobulin stain was positive in the cytoplasm of many clear cells and scattered colloid. This patient has been well without any evidence of recurrence over the past five years following surgery. The biological characteristics of clear cell carcinoma of the thyroid are discussed in this report.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Kniseley RM, Andrews GA. Transformation of thyroid carcinoma to clear cell type. Am J Clinical Path 1956; 26: 1427–1438.

    Google Scholar 

  2. Varrakojis D, Getz ML, Paloyan E, Straus FH. Papillary clear cell carcinoma of the thyroid gland. Human Pathology 1975; 6: 384–390.

    Google Scholar 

  3. Fisher ER, Kim WS. Primary clear cell thyroid carcinoma with squamous features. Cancer 1977; 39: 2497–2502.

    Article  PubMed  CAS  Google Scholar 

  4. Civantos F, Nadji M, Albores-Saavedra J, Morales A. Clear cell variant of thyroid carcinoma. Am J Surg Pathol 1984; 8: 187–192.

    Article  PubMed  CAS  Google Scholar 

  5. Kobayashi K, Suzuki A, Manabe Y, Ozaki O, Ito K. Clear cell tumor of the thyroid. J Jpan Soc Clin Surg 1987; 48: 154. (in Japanese)

    Google Scholar 

  6. Shambaugh GE, Quinn JL, Oyasu R, Freinkel N. Disparate thyroid imaging: Combined studies with sodium pertechnetate Tc 99m and radioactive iodine. JAMA 1974; 228: 866–869.

    Article  PubMed  Google Scholar 

  7. Atkins HL, Klopper JF, Lambrecht RM, Wolf AP. A comparison of technetium 99m and iodine 123 for thyroid imaging. Am J Roentgenol Radium Ther Nucl Med 1973; 117: 195–201.

    PubMed  CAS  Google Scholar 

  8. Chistensen SB, Bondeson L, Ericsson UB, Lindholm K. Prediction of malignancy in the solitary thyroid nodule by physical examination, thyroid scan, fine-needle biopsy and serum thyroglobulin. Acta Chir Scand 1984; 150: 433–439.

    Google Scholar 

  9. Koike A. Thyroid carcinoma and nodular goiter: Differential diagnosis and indication for surgical treatment of nodular goiter. J Aichi Med Univ 1975; 3: 169–176. (in Japanese)

    Google Scholar 

  10. Erjavec M, Movrin T, Auersperg M, Golouh R. Comparative accumulation of99mTc and131I in thyroid nodules: Case report. J Nucl Med 1977; 18: 346–347.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Koike, A., Naruse, T., Kanemitsu, T. et al. Clear cell carcinoma of the thyroid. A case report. The Japanese Journal of Surgery 19, 237–240 (1989). https://doi.org/10.1007/BF02471593

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02471593

Key words

Navigation