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Pure squamous cell carcinoma of the thyroid gland —rreport of an autopsy case and review of the literature—

The Japanese journal of surgery volume 18, pages 469–474 (1988)Cite this article

Abstract

A rare autopsy case of primary squamous cell carcinoma of the thyroid gland is reported herein. A 61-year-old Japanese woman with a swelling of the left neck underwent surgery and the resulting tumor was histopathologically diagnosed as pure squamous cell carcinoma of the thyroid gland. She had had the nodule for 20 years, and it was histologically diagnosed as having been a well-encapsulated, follicular adenoma. Histopathological observation of the resected glands also revealed the coexistence of pure squamous cell carcinoma, which presumably originated from the adenoma. Postoperatively, an esophagotracheal fistula formed due to local invasion of the tumor cells. The patient’s state gradually deteriorated and she died of severe bronchopneumonia and renal dysfunction, 4 months after the operation. Autopsy revealed no distant metastases, but severe septicemia caused by bacterial infection affecting the systemic organs was found, which presemably resulted in multiple organ failure.

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References

  1. Goldman RL. Primary squamous cell carcinoma of the thyroid gland: Report of a case and review of the literature. Am Surgeon 1964; 30: 247–252.

    PubMed  CAS  Google Scholar 

  2. Shimaoka K, Tsukada Y. Squamous cell carcinoma and adenosquamous carcinoma originating from the thyroid gland. Cancer 1980; 46: 1833–1842.

    PubMed  CAS  Article  Google Scholar 

  3. Harada T, Shimaoka K, Yakumaru K, Itoh K. Squamous cell carcinoma of the thyroid gland—transition from adenocarcinoma. J Surg Oncol 1982; 19: 36–43.

    PubMed  CAS  Google Scholar 

  4. Segal K, Sidi J, Abraham A, Konichezky M, Ben-Bassat M. Pure squamous cell carcinoma and mixed adenosquamous cell carcinoma of the thyroid gland. Head & Neck Surg 1984; 6: 1035–1042.

    CAS  Google Scholar 

  5. Huang T, Assor D. Primary squamous cell carcinoma of the thyroid gland: A report of four cases. Am J Clin Pathol 1971; 55: 93–98.

    PubMed  CAS  Google Scholar 

  6. Ackerman’s Surgical Pathology (Chapter 10: Gastrointestinal Tract/Esophagus: p. 400–415) The C.V. Mosby Company. St. Louis-Tronto-London. The sixth edition, 1981; 400–415.

  7. Block MA. Management of carcinoma of the thyroid. Ann Surg 1976; 185: 133–144.

    Article  Google Scholar 

  8. Aldinger KA. Anaplastic carcinoma of the thyroid. A review of 84 cases of spindle cell giant cell carcinoma of the thyroid. Cancer 1978; 41: 2267–2277.

    PubMed  CAS  Article  Google Scholar 

  9. Silverberg SG, Hutter RVP, Foote FW Jr. Fatal carcinoma of the thyroid: Histology, metastases, and causes of death. Cancer 1970; 25: 792–802.

    PubMed  CAS  Article  Google Scholar 

  10. Tsumori T, Nakao K, Kiyata M, Izukura M, Monden Y, Sakurai M, Kawashima Y, Nakahara K. Clinicopathologic study of thyroid carcinoma infiltrating the trachea. Cancer 1985; 56: 2843–2848.

    PubMed  CAS  Article  Google Scholar 

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Affiliations

  1. The First Department of Pathology, Hokkaido University School of Medicine, Kita 15, Nishi 7, Kita-ku, 060, Sapporo, Japan

    Jun Misonou & Miki Aizawa

  2. Department of Pathology, Asahikawa Municipal Hospital, Japan

    Makoto Kanda

  3. Department of Radiology, Asahikawa Municipal Hospital, Japan

    Youichi Uekita

  4. Department of Surgery, Asahikawa Municipal Hospital, Japan

    Toshiji Motohara

Authors
  1. Jun Misonou
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  2. Miki Aizawa
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  3. Makoto Kanda
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  4. Youichi Uekita
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  5. Toshiji Motohara
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Misonou, J., Aizawa, M., Kanda, M. et al. Pure squamous cell carcinoma of the thyroid gland —rreport of an autopsy case and review of the literature—. The Japanese Journal of Surgery 18, 469–474 (1988). https://doi.org/10.1007/BF02471475

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  • DOI: https://doi.org/10.1007/BF02471475

Key Words

  • thyroid neoplasm
  • squamous cell carcinoma
  • local recurrence