Carcinoma of the colon in children: Report of a case and review of the literature

  • Soichiro Takai
  • Manabu Yamamura
  • Michitomo Sakaguchi
  • Shoji Uetsuji
  • Masakatsu Yamamoto
Case Reports


Carcinoma of the colon seen in an 11-year-old boy is reported herein. The patient had advanced carcinoma of the ascending colon and died 8 months after an ileo-transversostomy had been performed as a palliative procedure. Histologically, the tumor was found to be signetring cell carcinoma. 29 cases of colon carcinoma reported in Japanese children under 15 years of age are also reviewed. In 19 of these patients, surgery was done as an elective procedure after the diagnosis of colon cancer had been established, but emergency surgery was performed on 10 patients for perforation or obstruction of the bowel. Curative resection was possible in 14 patients, but of these, only 3 patients survived for more than 10 years.

Key Words

childhood colon cancer acute abdomen barium enema mucin producing tumor 


  1. 1.
    Hoerner MT. Carcinoma of the colon and rectum in persons under twenty years of age. Am J Surg 1958; 96: 47–53.PubMedCrossRefGoogle Scholar
  2. 2.
    Goldman HS, Smith DL, Foote RF. Malignancies of the large intestine in persons less than 20 years old: Report of two cases. Dis Colon Rectum 1974; 17: 771–776.PubMedGoogle Scholar
  3. 3.
    Pratt CB, Rivera G, Shanks E, Johnson WW, Howarth C, Terrell W, Kumar APM. Colorectal carcinoma in adolescents; implications regarding etiology. Cancer 1977; 40: 2464–2472.PubMedCrossRefGoogle Scholar
  4. 4.
    Caldwell GG, Cannon SB, Pratt CB, Arthur RD. Serum Pesticide levels in patients with childhood colorectal carcinoma. Cancer 1981; 48: 774–778.PubMedCrossRefGoogle Scholar
  5. 5.
    Chabalko JJ, Fraumeni Jr JF. Colorectal cancer in children: Epidemiologic aspects. Dis Colon Rectum 1975; 18: 1–3.PubMedGoogle Scholar
  6. 6.
    Buchman JA, Calhoun JD. Colloid carcinoma of the colon in children. Am Surgeon 1958; 24: 280–286.PubMedGoogle Scholar
  7. 7.
    Bishop JF. Carcinoma of the colon in a boy 15 years of age: Report of a case. Dis Colon Rectum 1959; 4: 60–61.Google Scholar
  8. 8.
    Perkel LL, Alaghemand A. Carcinoma of the colon in children. Am J Proct 1962; 13: 170–173.PubMedGoogle Scholar
  9. 9.
    Middelkamp JN, Haffner H. Carcinoma of the colon in children. Pediatrics 1963; 32: 558–571.PubMedGoogle Scholar
  10. 10.
    Clutts GR, Emmett JM. Carcinoma of the colon in children under 16 years of age. Am Surgeon 1964; 30: 671–676.PubMedGoogle Scholar
  11. 11.
    Cain AS, Longino LA. Carcinoma of the colon in children. J Pediatr Surg 1970; 5: 527–532.PubMedCrossRefGoogle Scholar
  12. 12.
    Donaldson MH, Taylor P, Rawitscher R, Sewell Jr JB. Colon carcinoma in childhood. Pediatrics 1971; 48: 307–312.PubMedGoogle Scholar
  13. 13.
    Wolloch Y, Dintsman M. Carcinoma of the large intestine in children. Am J Surg 1974; 127: 693–695.PubMedCrossRefGoogle Scholar
  14. 14.
    Andersson A, Bergdahl L. Carcinoma of the colon in children: A report of six new cases and a review of the literature. J Pediatr Surg 1976; 11: 967–971.PubMedGoogle Scholar
  15. 15.
    Peltokallio P, Peltokallio V, Pasila M. Carcinoma of the rectum and colon in children: Report of three cases. Dis Colon Rectum 1968; 11: 193–197.PubMedCrossRefGoogle Scholar
  16. 16.
    Odone V, Chang L, Caces J, George SL, Pratt CB. The natural history of colorectal carcinoma in adolescents. Cancer 1982; 49: 1716–1720.PubMedCrossRefGoogle Scholar
  17. 17.
    Goldthorn JF, Powars D, Hays DM. Adenocarcinoma of the colon and rectum in the adolescent. Surgery 1983; 93: 409–414.PubMedGoogle Scholar
  18. 18.
    Heydenrych JJ, Warren B. An unusual presentation of carcinoma of the colon in a child: A case report. S Afr Med J 1984; 65: 617–618.PubMedGoogle Scholar
  19. 19.
    Rao BN, Pratt CB, Fleming ID, Dilawari RA, Green AA, Austin BA. Colon carcinoma in children and adolescents: A review of 30 cases. Cancer 1985; 55: 1322–1326.PubMedCrossRefGoogle Scholar
  20. 20.
    Ohta M, Iwafuchi M, Kuwayama T, Siraiwa K, Ohsawa Y, Soga J, Muto T. Carcinoma of the colon in child: A report of a case. J Jap Soc Pediatr Surg 1975; 10: 787–793.Google Scholar
  21. 21.
    Shibata A, Fuchigami T, Inoue M, Yamazaki A, Yoshizawa K. Carcinoma of the colon in children. Stomach Intestine 1981; 16: 697–701.Google Scholar
  22. 22.
    Uchiyama M. Personal communication, 1987.Google Scholar
  23. 23.
    Yamauchi M. Personal communication, 1986.Google Scholar
  24. 24.
    Takeda S. Personal communication, 1987.Google Scholar
  25. 25.
    Williams Jr C. Carcinoma of the colon in childhood. Ann Surg 1954; 139: 816–825.PubMedGoogle Scholar
  26. 26.
    Sessions RT, Riddell DH, Kaplan HJ, Foster JH. Carcinoma of the colon in the first two decades of life. Ann Surg 1965; 162: 279–284.PubMedGoogle Scholar
  27. 27.
    Koh SG, Johnson WW. Cancer of the large bowel in children. South Med J 1986; 79: 931–935.PubMedGoogle Scholar
  28. 28.
    Symonds DA, Vickery Jr AL. Mucinous carcinoma of the colon and rectum. Cancer 1976; 37: 1891–1900.PubMedCrossRefGoogle Scholar
  29. 29.
    Falterman KW, Hill CB, Markey JC, Fox JW, Cohn Jr IC. Cancer of the colon, rectum, and anus: A review of 2313 cases. Cancer 1974; 34: 951–959.PubMedCrossRefGoogle Scholar
  30. 30.
    O’Brien SE. Carcinoma of the colon in childhood and adolescence. Canad Med Ass J 1967; 96: 1217–1219.PubMedGoogle Scholar
  31. 31.
    Enker WE, Paloyan E, Kirsner JB. Carcinoma of the colon in the adolescent: A report of survival and an analysis of the literature. Am J Surg 1977; 133: 737–741.PubMedCrossRefGoogle Scholar
  32. 32.
    Caffarena PE, Dodero P, Magillo P, Soave F. Adenocarcinoma of the rectosigmoid colon in a 10-yr-old child. J Pediatr Surg 1981; 16: 87–89.PubMedGoogle Scholar

Copyright information

© The Japan Surgical Society 1988

Authors and Affiliations

  • Soichiro Takai
    • 1
  • Manabu Yamamura
    • 1
  • Michitomo Sakaguchi
    • 1
  • Shoji Uetsuji
    • 1
  • Masakatsu Yamamoto
    • 1
  1. 1.Department of SurgeryKansai Medical UniversityOsakaJapan

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