Abstract
Thirty-one Dacron double velour prostheses removed from 16 patients were studied microscopically in order to elucidate the changes they underwent following implantation. The process of incorporation was divided into three phases. In the initial phase, immediately following the implantation, the prostheses became surrounded by a fibrin meshwork. In the organizing phase, which sets in 10 weeks after the implantation, there was an external fibrous capsular formation around the initially fibrin-infiltrated grafts. There was also fibroblastic ingrowth and granulation formation among the interstices and the prostheses showed firm adhesion to the surrounding tissues. One year following the implantation, after most of the luminal surfaces had been covered with collagen tissues, the cellular infiltration subsided and the graft passed into the stable phase. Foreign body giant cells and lymphocytes were seen throughout the study period. These prostheses were then compared with other prostheses which do not have velour structures. The nonvelour grafts showed less adhesion to the surrounding tissues. Microscopically, cellular reaction and collagenous ingrowth were also less. The velour surface thus seems to stimulate granulation ingrowth and to contribute to the firm adhesion of the graft to the surrounding tissues. This firm adhesion enhances resistance to infection and is considered safer in case of suture aneurysm formation.
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Schafer PW, Hardin CA. The use of temporary polythene shunts to permit occlusion, resection, and frozen homologous graft replacement of vital vessel segments: a laboratory and clinical study. Surgery 1952; 31: 186–199.
Dubost C, Allary M, Oeconomos N. Resection of an aneurysm of the abdominal aorta: reestablishment of the continuity by a preserved human arterial graft, with result after five months. Arch Surg 1952; 64: 405–408.
Voorhees AB, Jaretzki A, Blakemore AH. The use of tubes constructed from vinyon “N” cloth in bridging arterial defects. Ann Surg 1952; 135: 332–336.
Turner RJ, Hoffmann HL, Weinberg SL. Knitted Dacron double velour grafts. In Stanley JC, ed. Biologic and Synthetic Vascular Prostheses, New York; Grune & Stratton, 1982; 509–522.
Hall CW, Liotta D, Ghidoni JJ, DeBakey ME, Dressler DP. Velour fabrics applied to medicine. J Biomed Mater Res 1969; 1: 179–196.
Sauvage LR, Berger KE, Wood SJ, Nakagawa Y, Mansfield PB. An external velour surface for porous arterial prostheses. Surgery 1971; 70: 940–953.
Noishiki Y, Yamane Y. Healing process of artificial vascular prostheses. Jinnkouzouki 1977; 6: 30–33. (in Japanese)
Lindenauer SM, Stanley JC, Zelenock GB, Cronewett JL, Whitehouse WM, Erlandson EE. Evaluation of Dacron double velour for arterial reconstruction. J Cardiovasc Surg 1981; 22: 518.
Kobayashi O. An experimental study of healing of velour grafts. Nippon Geka Gakkai Zasshi (J Jpn Surg Soc) 1986; 87: 211–219. (English Abst.)
Lindenauer SM, Lavanway JM, Fry WJ. Development of a velour vascular prostheses. Current Topics in Surgical Research 1970; 2: 491–503.
Hertzer NR. Regeneration of endothelium in knitted and velour Dacron vascular grafts in dogs. J Cardiovasc Surg 1981; 22: 223–230.
Clagett GP, Robinowitz M, Maddox Y, Langloss JM, Ramwell PW. The antithrombotic nature of vascular prosthetic pseudointima. Surgery 1982; 91: 87–94.
Sauvage LR, Berger KE, Wood SJ, Yates SG, Smith JC, Mansfield PB. Interspecies healing of porous arterial prostheses: observations, 1960 to 1974. Arch Surg 1974; 109: 698–705.
Sauvage LR, Berger K, Beilin LB, Smith JC, Wood SJ, Mansfield PB. Presence of endothelium in an axillary-femoral graft of knitted Dacron with an external velour surface. Ann Surg 1975; 182: 749–753.
Berger K, Sauvage LR, Rao AM, Wood SJ. Healing of arterial prostheses in man: its incompleteness. Ann Surg 1972; 175: 118–127.
DeBakey ME, Jordan GL, Beall AC, O’Neal RM, Abbott JP, Halpert B. Basic biologic reactions to vascular grafts and prostheses. Surg Clin North Am 1965; 45: 477–497.
Malone JM, Moore WS, Campagna G, Bean B. Bacteremic infectability of vascular grafts: the influence of pseudointimal integrity and duration of graft function. Surgery 1975; 78: 211–216.
Moore WS, Malone JM, Keown K. Prosthetic arterial material: influence of neointimal healing and bacteremic infectability. Arch Surg 1980; 115: 1379–1383.
Mitchell RS, Miller DC, Billingham ME, Mehigan JT, Olcott C, Stinson EB. Comprehensive assessment of the safety, durability, clinical performance, and healing characteristics of a double velour knitted Dacron arterial prosthesis. Vasc Surg 1980; 14: 197–212.
Fuse K. A histopathological study of the synthetic vascular prostheses recovered from thirty-two clinical cases. Nippon Geka Gakkai Zasshi (J Jpn Surg Soc) 1977; 78: 473–494. (English Abst.)
Sato O, Kohzuma T, Tada Y. Abdominal aortic aneurysm. Medicina 1985; 22: 2386–2389. (in Japanese)
DeBakey ME, Jordan GL, Abbot JP, Halpert B, O’Neal RM. The fate of Dacron vascular grafts. Arch Surg 1964; 89: 757–782.
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Sato, O., Tada, Y. & Takagi, A. The biologic fate of Dacron double velour vascular prostheses —A clinicopathological study—. The Japanese Journal of Surgery 19, 301–311 (1989). https://doi.org/10.1007/BF02471406
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DOI: https://doi.org/10.1007/BF02471406