Abstract
The syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is commonly observed in patients with bronchogenic carcinoma. We report here a rare case of SIADH induced by rectal cancer. Laboratory findings showed that the serum sodium concentration and serum osmolarity were low, and that the ADH level was high. Resection of the rectal cancer resulted in a complete correction of the associated inappropriate ADH. The titer of the rectal cancer tissue proved to be high (80 pg/g).
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Schwarts WB, Bennet W, Curelop S, Bartter FC. A syndrome of rectal sodium loss and hyponatremia probably resulting from inappropriate secretion of antidiuretic hormone. Am J Med 1957; 23: 529–542.
Vossi S, Baardsen A. The syndrome of inappropriate secretion of antidiuretic hormone (SIADH). Acta Chr Scand 1981; 147: 159–160.
Suzuki H, Tsutsumi Y, Yamaguchi K, Abe K, Yokoyama T. Small cell lung carcinoma with ectopic adrenocorticotrophic hormone and antidiuretic hormone syndromes. Jpn J Clin Oncol 1984; 14: 129–137.
Epstein S, Ranchod M, Goldswain P. Pituitary insufficiency, inappropriate antidiuretic hormone (ADH) secretion, and carcinoma of the bronchus. Cancer 1973; 32: 476–481.
Maze SS, Klaff LJ, Yach D. Syndrome of inappropriate antidiuretic hormone secretion in association with herpes zoster of the chest wall. S Afr Med J 1983; 63: 735–736.
Takabayashi K, Hasegawa K, Nakamura K, Morohashi Y, Saeki S, Ito K, Kanai H. A case of an ectopic antidiuretic hormone (ADH) producing pancreas carcinoma. Chiba Igaku 1978; 54: 103–108. (in Japanese)
Levin L, Sealy R, Barron J. Syndrome of inappropriate antidiuretic hormone secretion following Cis-Dichlorodiammineplatium 2 in a patient with malignant thymoma. Cancer 1982; 50: 2279–2282.
Takahashi T, Akisawa T, Koshikawa S, Kinebuchi M, Suzuki K, Simizu S. Inappropriate antidiuretic hormone secretion associated with rectum carcinoma. Jin To Tohseki 1980; 8: 81–84. (in Japanese)
Bartter FC, Schwarts WB. The syndrome of inappropriate secretion of antidiuretic hormone. Am J Med 1967; 42: 790–806.
Craig TC. Correction of an inappropriate ADH syndrome by tumor resection. Arch Inter Med 1968; 121: 163–169.
Greenbaum LD, Rosenstock JG, Belasco LB, Rohrbaugh TM, Meadows AT. Syndrome of inappropriate antidiuretic hormone secretion. Cancer 1985; 55: 44–46.
Yoshida S. Antidiuretic hormone producing tumors. Gan to Kagaku Ryoho (Jpn J Cancer Chemo) 1976; 3: 631–634. (in Japanese)
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Murakami, S., Togo, S., Yasuda, S. et al. The syndrome of inappropriate secretion of antidiuretic hormone by rectal cancer —A case report—. The Japanese Journal of Surgery 17, 293–296 (1987). https://doi.org/10.1007/BF02470703
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02470703