Advertisement

The Japanese journal of surgery

, Volume 14, Issue 6, pp 486–493 | Cite as

Hepatic resection for primary liver malignancy

  • Yoshio Kinami
  • Koji Shinmura
  • Itsuo Miyazaki
Original Articles

Abstract

The results of hepatic resection for patients with primary liver malignancy seen at our clinic during the past 21 years are reported. Of 92 patients, 57 had cirrhosis in addition to hepatocellular carcinoma, and 49 (53 percent) underwent hepatic resection of various degrees from partial resection to trisegmentectomy. Resectability rates of the liver were 52 percent in 77 patients with hepatocellular carcinoma, including 19 in whom the tumor was less than 5 cm in diameter, and 60 percent in 15 patients with other malignant tumors; operative mortality rates were 15 percent in the former and 0 percent in the latter. Cumulative survival rates of all patients who underwent hepatic resection, excluding death within one month, were 55 percent at one year, 29 at 3 and 5 years. In patients with hepatocellularcarcinoma, survival rates of 15 those who had a curative resection of the tumor were 87 percent at one year and 47 percent at 3 or 5 years, there was a significant difference in survival curves between those with tumors less than 5 cm and more than 5 cm (p<0.05). On the other hand, survival rates of all patients with other malignant tumors were 78 percent at one year and 37 percent at 5 years. These results indicate the importance of performing hepatic resection for patients with small hepatocellular carcinoma associated with cirrhosis and those with other malignant tumors.

Key Words

primary liver malignancy hepatocellular carcinoma liver cirrhosis 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Liver Cancer Study Group of Japan. Survey and follow-up study of primary liver cancer in Japan-report 5. Acta Hepatologica Japonica 1982; 23: 675–681. (in Japanese)CrossRefGoogle Scholar
  2. 2.
    Iwatsuki S, Shaw B B, Starzl T E. Experience with 150 liver resections. Ann Surg 1983; 197: 247–253.CrossRefPubMedPubMedCentralGoogle Scholar
  3. 3.
    Kasai Y, Tsuchiya R, Treatment of hepatoma associated with cirrhosis. J Jpn Surg Soc 1978; 79: 901. (in Japanese)Google Scholar
  4. 4.
    Sugahara K, Kawano N, Nagao T. Evaluation of preoperative findings aids in the management of liver cancer. Gastroenterological Surgery 1982; 5: 413–422. (in Japanese)Google Scholar
  5. 5.
    Foster J H. Survival after liver resection for cancer. Cancer 1970; 26: 493–502.CrossRefPubMedGoogle Scholar
  6. 6.
    Lee N W, Wong J, Ong G B. The surgical management of primary carcinoma of the liver. World J Surg 1982; 6: 66–75.CrossRefPubMedGoogle Scholar
  7. 7.
    Almersjö O, Bengmark S, Hafström Lo. Liver resection for cancer. Acta Chir Scand 1976; 142: 139–144.PubMedGoogle Scholar
  8. 8.
    Curutchet H P, Terz J J, Kay S, Lawrence W Jr. Primary liver cancer, Surgery 1971; 70: 467–479.PubMedGoogle Scholar
  9. 9.
    McBride C M. Primary carcinoma of the liver. Surgery 1976; 80: 322–327.PubMedGoogle Scholar
  10. 10.
    Bengmark S, Hafström L, Jeppsson B, Sundgvist K. Primary carcinoma of the liver: improvement in sight? World J Surg 1982; 6: 54–60.CrossRefPubMedGoogle Scholar
  11. 11.
    Balasegaram M. Management of primary liver cell carcinoma. Am J Surg 1975; 130: 33–37.CrossRefPubMedGoogle Scholar
  12. 12.
    Honjo I, Mizumoto R. Primary carcinoma of the liver. Am J Surg 1974; 128: 31–36.CrossRefPubMedGoogle Scholar
  13. 13.
    Okuda K, the Liver Cancer Study Group of Japan. Primary liver cancers in Japan. Cancer 1980; 45: 2663–2669.CrossRefGoogle Scholar
  14. 14.
    Ozawa K. Treatment for cirrhotic liver cancer J. Jpn Surg Soc 1978; 79: 654–657. (in Japanese)Google Scholar
  15. 15.
    Kinami Y, Shinmura K, Izumi R, Takada M, Sugahara S, Sakuma K, Sakata N, Kurachi M, Miyazaki I. Study on clinical and pathological findings of patients with minute hepatocellular carcinoma. Acta Hepatologica Japonica 1982; 23: 1397–1402. (in Japanese)CrossRefGoogle Scholar
  16. 16.
    Balasegaram M, Joisky S K. Hepatic resection, pillars of success built on the foundation of 15 years of experience. Am J Surg 1981; 141: 360–365.CrossRefPubMedGoogle Scholar
  17. 17.
    Lin T. Recent advances in technique of hepatic lobectomy and results of surgical treatment for primary carcinoma of the liver. Prog Liver Dis 1976; 5: 668–682.PubMedGoogle Scholar
  18. 18.
    Liver Cancer Study Group of Japan. Survey and follow-up study of primary liver cancer in Japan-report 4. Acta Hepatologica Japonica 1979; 20; 433–441. (in Japanese)CrossRefGoogle Scholar
  19. 19.
    Tsuzuki, Ogata Y, Shimazu M, Matsubara S, Takenaka Y, Kurihara E, Yoshii H. Surgical management of hepatoma, Rinshio Seijinbyo 1980; 10: 1003–1011. (in Japanese)Google Scholar
  20. 20.
    Fukui M, Kusano S, Matama S, Murata K, Shibata H. A critical evaluation of various treatments for hepatocellular carcinoma. Japanese J Gastroent 1983; 80: 1450–1460. (in Japanese)Google Scholar

Copyright information

© The Japan Surgical Society 1984

Authors and Affiliations

  • Yoshio Kinami
    • 2
  • Koji Shinmura
    • 1
  • Itsuo Miyazaki
    • 1
  1. 1.The Second Department of SurgeryKanazawa University School of MedicineKanazawaJapan
  2. 2.The Second Department of SurgeryKanazawa Medical UniversityKahoku-Gun, Ishikawa-kenJapan

Personalised recommendations