Abstract
We noted a marked improvement of lymphedema in a patient with recurrence of cancer 3 years after amputatio recti and with post-thrombotic syndrome of the leg, as the result of injection of a suspension of lymphocytes administrated as therapy against advanced cancer. Subsequently lymphocytes-injections were given 39 times to 7 patients with lymphedema of one limb, of various causes. A suspension of lymphocytes was injected repeatedly into the proximal artery of the affected limb. In one patient, lymphocytes were injected 4 times at intervals of 1 or 3 weeks. In most cases, this injection resulted in a marked reduction in the swelling of the affected limb and improvement was seen for several weeks or months. In all cases, there was a marked, continuous softening of the tissue.
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Katoh, I., Harada, K., Tsuda, Y. et al. Intraarterial lymphocytes injection for treatment of lymphedema. The Japanese Journal of Surgery 14, 331–334 (1984). https://doi.org/10.1007/BF02469651
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DOI: https://doi.org/10.1007/BF02469651