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Effects of hemodynamic changes induced by hyper- or hypothermia on intravenous lipid clearance rate and lipoprotein lipase activity in dogs

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Abstract

Hyper- and hypothermia was induced in dogs by peritoneal perfusion with warm or cold Lactate-Ringer's solution, the objective being to alter cardiac output. Changes in cardiac index, intravenous lipid clearance rate (K-value), and lipoprotein lipase (LPL) activity, concomitantly with changes of the temperature of the mixed venous blood were investigated. The cardiac index increased significantly with the hyperthermia and there was a close correlation between the cardiac index and the K-value. The LPL activity did not change significantly with changes in blood temperature, and the correlation between the LPL activity and the K-value was not significant. The hemodynamics has to be considered when attempting to discuss the intravenous lipid clearance rate.

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References

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Authors and Affiliations

  1. The Second Department of Surgery, Mie University School of Medicine, 2-174 Edobashi, 514, Tsu, Japan

    Hiroshi Nishiwaki, Keiji Iriyama, Noriko Kusaka, Tadashi Teranishi & Hiroshi Mori

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  1. Hiroshi Nishiwaki
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  2. Keiji Iriyama
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  3. Noriko Kusaka
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  4. Tadashi Teranishi
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  5. Hiroshi Mori
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Nishiwaki, H., Iriyama, K., Kusaka, N. et al. Effects of hemodynamic changes induced by hyper- or hypothermia on intravenous lipid clearance rate and lipoprotein lipase activity in dogs. The Japanese Journal of Surgery 13, 543–545 (1983). https://doi.org/10.1007/BF02469501

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  • DOI: https://doi.org/10.1007/BF02469501

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