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Pathogenesis and treatment of metabolic acidosis in open heart surgery under surface induced deep hypothermia

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Abstract

Metabolic acidosis observed in open heart surgery under surface induced deep hypothermia is due to lactacidemia, but is reversible, returning to precooling level 24 hours after the operation, and it can be considered more or less as a pathognomonic finding. Although the correction of acidosis present did not influence the level of lactic acid in blood, it was found to be clinically advantageous during the heartresuscitation. Therefore, it is advisable to maintain acid-base balance within-10 mEq per 1 of base excess.

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References

  1. Ballinger II, W. F., Vollenweider, H., Templeton III, J. Y. and Pierucci Jr. L.: Acidosis of Hypothermia, Ann. Surg. 154: 517–523, 1961

    Article  CAS  PubMed  Google Scholar 

  2. Brewin, E. G.: An Investigation of Problems of Acid Base Equilibrium in Hypothermia, Guy's Hospital Reports 104: 177–214, 1955.

    PubMed  CAS  Google Scholar 

  3. Bigelow, W. G.: Hypothermia—Its Possible Role in Cardiac Surgery, Ann. Surg. 132: 849–866, 1950.

    PubMed  CAS  Google Scholar 

  4. Broder, G and Weil, M. H.: Excess Lactate: An Index of Reversibility of Shock in Human Patients, Science 143: 1457–1459, 1964.

    PubMed  CAS  Google Scholar 

  5. Isayama, T.: Experimental Studies on the Profound Hypothermia from a View Point of the Acid Base Balance in the Whole Blood, Nihon Geka Gakkai Zasshi (Journal of Japan Surgical Sociaty) 73: 397–423, 1972 (in Japanese).

    Google Scholar 

  6. Peretz, D. I., Scott, H. M., Duff, J., Dossefor, J. B., MacLean, L. D. and McGregor, M.: The Significance of Lactic Acidemia in the Shock Syndrome, Ann. N. Y. Acad. Sci. 119: 1133–1140, 1965.

    PubMed  CAS  Google Scholar 

  7. Richterich, R.: Clinical Chemistry. pp. 219–223, Academic Press, N. Y. & London, 1969.

    Google Scholar 

  8. Shida, H., Ikeda, S., Morimoto, M., Tsuchiya, T. and Seki, T.: Changes of Acid Base Balance in Open Heart Surgery by Simple Profound Hypothermia, Kyobu Geka (J. Thorac. Surg.) 25: 353–357, 1972 (in Japanese with English summary).

    PubMed  CAS  Google Scholar 

  9. Vitek, V. and Cowley, R. A.: Blood Lactate in the Prognosis of Various Forms of Shock, Ann. Surg. 173: 308–313, 1971.

    PubMed  CAS  Google Scholar 

  10. Walker, A. W.: Renal Response to Hypothermia, Clin. Chim. Acta. 14: 462–474, 1966.

    Article  PubMed  CAS  Google Scholar 

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Shida, H. Pathogenesis and treatment of metabolic acidosis in open heart surgery under surface induced deep hypothermia. The Japanese Journal of Surgery 4, 198–203 (1974). https://doi.org/10.1007/BF02469452

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