Abstract
A case of fibrosarcoma arising in the scar of the radical mastectomy with postoperative irradiation of breast carcinoma is reported. The tumors arose five times in spite of the extirpations including surrounding tissue since 11 years after radical mastectomy and postoperative irradiation. All of arisen tumors were diagnosed fibrosarcoma histologically and with every recurrence the aggrevation of malignancy of tumors was shown. In this case, the primary tumor of the breast was infiltrating carcinoma and no sign of fibrosarcoma was noted histologically. The mastectomy scar was indicated the irradiation therapy postoperatively and fibrosarcoma developed 11 years after postoperative irradiation. Namely, this case agreed to the strict criteria of the postirradiation sarcoma proposed by Cahan et al. In this paper, a case of postirradiation fibrosarcoma arising in the scar of radical mastectomy for carcinoma is presented.
Similar content being viewed by others
References
Barnett, W.O., Hardy, J.D. and Hendrix, J.H.: Lymphangiosarcoma following postmastectomy lymphedema,Ann. Surg. 6: 960–968, 1969.
Cahan, W.G., Woodard, H.Q., Higinbotham, N.L., Stewart, F.W. and Coley, B.L.: Sarcoma arising in irradiated bone. Report of elevent cases,Cancer 1: 3–29, 1948.
Hatfield, P.M. and Schulz, M.D.: Postirradiation sarcoma including 5 cases after X-ray therapy of breast carcinoma,Radiology 96: 593–602, 1970.
Oberman, H.A. and Oneal, R.M.: Fibrosarcoma of the chest wall following resection and irradiation of carcinoma of the breast,Amer. J. Clin. Path. 53: 407–412, 1970.
Rachmaninoff, N., McDonald, J.R. and Cook, J.C.: Sarcomalike tumors of the skin following irradiation,Amer. J. Clin. Path. 36: 427–437, 1961.
Sarrazin, D. Contesso, G. and Genin, J.: Les fibrosarcomes de laparoi thoracique survenus aprés chirurgie et irradiation d'une tumeur mammaire. Presentation de quatre cas,Ann. Radiol. 15: 667–675, 1972.
Schwartz, E.E. and Rothstein, J.D.: Fibrosarcoma following radiation therapy,J.A.M.A. 203: 134–136, 1968.
Shirger, A.: Postoperative lymphedema: Etiologic and diagnostic factors,Med. Clin. N. Amer. 46: 1045–1050, 1962.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Iwasaki, K., Nagamitsu, S. & Tsuneyoshi, M. Postirradiation fibrosarcoma following radical mastectomy. The Japanese Journal of Surgery 8, 73–77 (1978). https://doi.org/10.1007/BF02469338
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02469338