Summary
CE is used both for routine clinical analysis and for specialized clinical investigations. CE analysis of serum proteins is fast and reliable, with immunosubtraction for identification of immunoglobulins. This method was used to show the appearance of a pathological protein many years prior to the diagnosis of myelomatosis. CE with diode array detector and CE-MS were suitable for the diagnosis of a number of metabolic disorders. Online analyte concentrators are sometimes required to enhance the concentration sensitivity of CE.
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References
E. Jellum, H. Dollekamp, C. Blessum, J. Chromatogr. B.683, 55 (1996).
E. Jellum, H. Dollekamp, A. Brunsvig, R. Gislefoss, J. Chromatogr. B.689, 155 (1997).
S. H. Kang, J. W. Kim, D. S. Chung, Pharm. Biomed. Anal.9–10, 1435 (1997).
J. Schneede, P. M. Ueland, Anal. Chem.67, 802 (1995).
D. B. Marsh, D. B. L. Nutall, J. Capil. Electrophor.2, 63 (1995).
J. M. Hempe, J. N. Granger, R. D. Craver, Electrophoresis10, 1785 (1997).
R. P. Oda, R. Clark, J. A. Katzmann, J. P. Landers, Electrophoresis10, 1709 (1997).
P. G. Righetti, C. Gelfi, J. Chromatogr. B.697, 195 (1997).
G. Schmitz, C. Mollers, V. og. Richter, Electrophoresis10, 1807 (1997).
K. P. Presto Elgstoen, E. Jellum, Electrophoresis18, 1857 (1997).
A. J. Tomlinson, N. A. Guzman, S. Naylor, J. Capil. Electrophor.2, 247 (1995).
N. A. Guzman, S. S. Park, D. Schaufelberger, L. Hernandez, X. Paez, P. Rada, A. T. Tomlinson, S. Naylor, J. Chromatogr. B.697, 37 (1997).
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Presto Elgstoen, K.B., Gislefoss, R. & Jellum, E. Recent advances in the clinical applications of capillary electrophoresis. Chromatographia 49 (Suppl 1), S79–S80 (1999). https://doi.org/10.1007/BF02468980
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DOI: https://doi.org/10.1007/BF02468980