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Remnant liver function during surgery for extensive hepatic resection

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Abstract

True functional reserve of remnant liver should be determined at the same condition that contemplated hepatectomy has been performed, and this condition can be achieved before resection by temporary lamping of the inflow vessels of hepatic lobes to be removed. Using indocyanine green (ICG), the remnant liver function (RLF) was evaluated whether or not the method can be a useful indicator for or against hepatomy. In the study of healthy dogs, the RLF proved to be a reliable indicator to prospect hepatic failure which may occur after extensive resection of the liver. Then, the method was employed in nine patients who underwent 40 to 70 per cent hepatectomy. The results indicated that the RLF with ICG during surgery, if performed under stable hemodynamics, is a beneficial tool to decide the resectability in equivocal cases.

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References

  1. Almersjo, O., Bengmark, S., Hafstrom, L. O., and Olsson, R.: Enzyme and functional changes after extensive liver resection in man,Ann. Surg. 169: 111–119, 1969.

    PubMed  CAS  Google Scholar 

  2. Aronsen, K. F., Ericsson, B. and Phil, B.: Metabolic changes following major hepatic resection,ann. Surg. 169: 102–110, 1969.

    PubMed  CAS  Google Scholar 

  3. Balasegaram, M.: Management of primary liver cell carcinoma,Am. J. Surg. 130: 33–37, 1975.

    Article  PubMed  CAS  Google Scholar 

  4. Lin, T. Y. and Chen, C. C.: Metabolic function and regeneration of cirrhotic and non-cirrhotic livers after hepatic lobectomy in man,Ann. Surg. 162: 959–972, 1965.

    PubMed  CAS  Google Scholar 

  5. Lin, T. Y.: Personal communication.

  6. McDermott, W. V., Jr., Greenberger, N. J., Isselbacher, K. J., and Weber, A. L.: Major hepatic resection; diagnostic techniques and metabolic problems,Surgery 54: 56–66, 1963.

    Google Scholar 

  7. Monaco, A. P., Hallgrimsson, J. and McDermott, W. V., Jr.: Multiple adenoma (hamartoma) of the liver treated by subtotal (90%) resection: Morphological and functional studies of regeneration,Ann. Surg. 159: 513–519, 1964.

    Article  PubMed  CAS  Google Scholar 

  8. Nagasue, N., Inokuchi, K., Kobayashi, M., Ogawa, Y., Saku, M., Iwaki, A. and Yukaya, H.: Angiographic evaluation of hepatoma for surgical treatment,Surg. Gynecol. Obstet. 143: 184–190, 1976.

    PubMed  CAS  Google Scholar 

  9. Nagasue, N., Inokuchi, K., Kobayashi, M., Ogawa, Y., Iwaki, A. and Yukaya, H.: Hepatic dearterialization for nonresectable primary and secondary tumors of the liver,Cancer 38: 2593–2603, 1976.

    Article  PubMed  CAS  Google Scholar 

  10. Ozawa, K., Yamaoka, Y., Kitamura, O., Nambu, H., Kamiyama, Y., Takeda, O., Takasan, H. and Honjo, I.: Clinical application of cytochrome a (+a3) assay of mitochondria from liver specimens: An aid in determining metabolic tolerance of liver ramnant for hepatic resection,Ann. Surg. 180: 868–876, 1974.

    Article  PubMed  CAS  Google Scholar 

  11. Pack, G. T. and Molander, D. W.: Metabolism before and after hepatic lobectomy for cancer,Arch. Surg. 80: 685–692, 1960.

    PubMed  CAS  Google Scholar 

  12. Sigel, B.: Partial hepatectomy in the dog,Arch. Surg. 80: 100–103, 1963.

    Google Scholar 

  13. Starzl, T. E., Putnam, C. W., Groth, C. G., Corman, J. L. and Taubman, J.: Alopecia, ascites, and incomplete regeneration after 85 to 90 per cent liver resection,Am. J. Surg. 129: 587–590, 1975.

    Article  PubMed  CAS  Google Scholar 

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Nagasue, N., Inokuchi, K., Iwaki, A. et al. Remnant liver function during surgery for extensive hepatic resection. The Japanese Journal of Surgery 9, 125–131 (1979). https://doi.org/10.1007/BF02468847

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