Abstract
A clinicopathological study of gastric carcinoma was carried out according to Lauren's classification, on 207 patients, who underwent gastric resection at Department of Surgery II, Kyushu University, Faculty of Medicine from 1970 to 1972. Among them 93 cases (44.9%) were of intestinal-type carcinoma, 71 (34.3%) of diffuse carcinoma and 43 (20.8%) of other types. Intestinal-type carcinoma, often showing the protuberant type, was more common in the aged and in men. Most had a low grade of penetration, while in some, the penetration was moderate to high grade and was associated with lymph node metastasis, lymphatic and vascular involvement, or liver metastasis. Hematogenous recurrence was not infrequent.
Diffuse carcinoma was more common in younger subjects and women, and was often of the depressed type. The serosa was involved in most cases. High grade penetration was associated with lymphatic permeation. Metastasisvia the bloodstream was infrequent. Recurrence was often due to peritoneal dissemination. A better prognosis was indicated in cases of diffuse carcinoma with no serosal involvement, while prognosis in cases of invasion of the serosa was worse for diffuse carcinoma than for intestinal-type carcinoma.
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References
Correa, P., Sasano, N., Stemmermann, G.N. and Haenszel, W.: Pathology of gastric carcinoma in Japanese populations: Comparisons between Miyagi Prefecture, Japan, and Hawaii. J. Nat. Cancer Inst., 51: 1449–1457, 1973.
Heilmann, K., Burkhardt, H.U. and Kaysen, K.: Der intestinale und diffuse Typ des Magenkarzinoms. Zeitschrift für Gastroenterologie, 16: 422–430, 1978.
Iwanaga, T. and Furukawa, Y.: Histopathological observation on progression of gastric cancer. Shokaki Geka (Gastroenterological Surgery), 2: 301–309, 1979 (in Japanese).
Japanese Research Society for Gastric Cancer: The general rules for the gastric cancer. Jap. J. Surgery, 3: 61–71, 1973.
Kakizaki, G., Fujiwara, Y., Kato, E., Saito, T., Maeta, T., Ishidate, T. and Ono, I.: Significance of Lauren's classification in chemotherapy of gastric carcinoma. Tohoku J. exp. Med., 119: 41–49, 1976.
Lauren, P.: The two histological main types of gastric carcinoma: Diffuse and so-called intestinal-type carcinoma. Acta path. et microbiol. Scandinav., 64: 31–49, 1965.
Munoz, N. and Asvall, J.: Time trends of intestinal and diffuse types of gastric cancer in Norway. Int. J. Cancer 8: 144–157, 1971.
Nakamura, K., Sugano, H., Takagi, K. and Kumakura, K.: Conception of histogenesis of gastric cancer. I to Cho (Stomach and Intestine) 6: 849–861, 1971 (Eng. Abs.).
Noda, S.: Histological classification of gastric carcinoma. Gan no Rinsho (Japan J. Cancer Clinics) 16: 786–797, 1970 (in Japanese).
Soejima, K.: Gastric cancer recurrence, review of 21 cases examined at autopsy. Fukuoka Igaku Zasshi (Fukuoka acta medica) 55: 410–430, 1964 (Eng. Abs.).
Stemmermann, G.N. and Brown, G.: A survival study of intestinal and diffuse types of gastric carcinoma. Cancer 33: 1190–1195, 1974.
Yamamoto, T. and Kato, H.: Two major histological types of gastric carcinoma among the fixed population of Hiroshima and Nagasaki. GANN 62: 381–387, 1971.
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Noda, S., Soejima, K. & Inokuchi, K. Clinicopathological analysis of the intestinal type and diffuse type of gastric carcinoma. The Japanese Journal of Surgery 10, 277–283 (1980). https://doi.org/10.1007/BF02468788
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DOI: https://doi.org/10.1007/BF02468788