The Japanese journal of surgery

, Volume 4, Issue 3, pp 165–174 | Cite as

Simultaneous occurrence of multiple gastric carcinomas and familial polyposis of the colon

  • Keiichi Ohsato
  • Hidenobu Watanabe
  • Hideaki Itoh
  • Tsuneyoshi Yao
  • Masaya Nishimura
Article

Abstract

Upper gastrointestinal survey in ten patients with familial polyposis of the colon revealed the presence of polyps and/or carcinomas of the stomach or duodenum in eight, including two cases of associated multiple gastric carcinomas with concomitant presence in one case of multiple gastroduodenal adenomatous polyps and in the other without presence of polyp. The rather frequent association of gastroduodenal polyps and cancerous lesions in familial polyposis suggests such association to be a part of the manifestation of this inherited disease and possible malignant change occurring in gastroduodenal mucosa as is generally supposed to be the case in large intestine.

Key Words

familial polyposis multiple gastric cancers polyp upper gastrointestinal survey total colectomy gastrectomy gastrointestinal cripples 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Boley, S. J., McKinnon, W. M. P., and Marzulli, V. F.: The management of familial gastrointestinal polyposis involving stomach and colon, Surgery, 50: 691–696, 1961.PubMedGoogle Scholar
  2. 2.
    Cabot, R. C.: Case records of the Massachusetts General Hospital, Case 21061, New Engl. J. Med. 212: 263–267, 1935.CrossRefGoogle Scholar
  3. 3.
    Capps, W. F. Jr., Lewis, M. I., and Gazzaniga, D. A.: Carcinoma of the colon, ampulla of Vater and urinary bladder associated with familial multiple polyposis: A case report, Dis. Colon Rectum 11: 298–305, 1968.PubMedGoogle Scholar
  4. 4.
    Coli, R. D., Moore, J. P., La Marche, P. H., DeLuca, F. G., and Thayer, W. R. Jr.: Gardner's syndrome, A revisit to a previously described family, Digestive Disease 15: 551–568, 1970.CrossRefGoogle Scholar
  5. 5.
    Devic, A., and Bussy: Un cas de polypose adenomateuse generalisee a tout l'intestin, Arch. Fr. Mal. Appl. Dig. 6: 278–299, 1912.Google Scholar
  6. 6.
    Dukes, C. E.: Cancer control in familial polyposis of the colon, Dis. Colon Rectum 1: 413–423, 1958.PubMedGoogle Scholar
  7. 7.
    Duncan, B. R., Dohner, V. A., and Priest, J. H.: The Gardner syndrome: Need for early diagnosis, J. Pediat. 72: 497–505, 1968.PubMedCrossRefGoogle Scholar
  8. 8.
    Gardner, E. J., and Richards, R. C.: Multiple cutaneous and subcutaneous lesions occuring simultaneously with hereditary polyposis and osteomatosis, Amer. J. Human Genet. 5: 139–147, 1953.Google Scholar
  9. 9.
    Halsted, J. A., Harris, E. J., and Bartlett, M. K.: Involvement of the stomach in familial polyposis of the gastrointestinal tract, Report of a family, Gastroenterology 15: 763–770, 1950.PubMedGoogle Scholar
  10. 10.
    Hoffmann, D. C., and Goligher, J. C.: Polyposis of the stomach and small intestine in association with familial polyposis coli, Brit. J. Surg. 58: 126–128, 1971.PubMedGoogle Scholar
  11. 11.
    Lockhart-Mummery, J. P., and Dukes, C. E.: Familial adenomatosis of colon and rectum, its relation to cancer, Lancet 2: 586–589, 1939.CrossRefGoogle Scholar
  12. 12.
    Macdonald, J. M., Davis, W. C., Crago, H. R., and Berk, A. D.: Gardner's syndrome and periampullary malignancy, Amer. J. Surg. 113: 425–430, 1967.PubMedCrossRefGoogle Scholar
  13. 13.
    Mayo, C. W., DeWeerd, J. H., and Jackman, R. J.: Diffuse familial polyposis of the colon, Surg. Gynec. Obstet. 93: 87–96, 1951.PubMedGoogle Scholar
  14. 14.
    McFarland, P. H. Jr, Scheetz, W. L., and Knisley, R. E.: Gardner's syndrome: Report of two families, J. Oral. Surg. 26: 632–638, 1968.PubMedGoogle Scholar
  15. 15.
    Melmed, R. N., and Bouchier, I. A. D.: Duodenal involvement in Gardner's syndrome, Gut 13: 524–527, 1972.PubMedGoogle Scholar
  16. 16.
    Moertel, C. G., Bargen, J. A., and Soule, E. H.: Multiple gastric cancers: Review of the literature and study of 42 cases, Gastroenterology 32: 1095–1102, 1957.PubMedGoogle Scholar
  17. 17.
    Murphy, E. S., Mireles, M. V., and Beltran, A. O.: Familial polyposis of the colon and gastric carcinoma: Concurrent conditions in a 16-year-old boy, JAMA 179: 1026–1028, 1962.PubMedGoogle Scholar
  18. 18.
    Parks, T. G., Bussey, H. J. R., and Lockhart-Mummery, H. E.: Familial polyposis coli associated with extracolonic abnormalities, Gut 11: 323–329, 1970.PubMedGoogle Scholar
  19. 19.
    Pollack, J. L., and Swinton, N. W.: Congenital polyposis of the colon with extension to the small intestine and stomach, Lahey Clinic Faundation Bulletin 9: 174–179, 1955.Google Scholar
  20. 20.
    Schnur, P. L., David, E., Brown, P. W. Jr, Beahrs, O. H., ReMine, W. H., and Harrison, E. G. Jr: Adenocarcinoma of the duodenum and the Gardner syndrome, JAMA 223: 1229–1232, 1973.PubMedCrossRefGoogle Scholar
  21. 21.
    Utsunomiya, J., Maki, T., Iwama, T., Matsunaga, Y., Shinomura, T., Ichikawa, T., Hamaguchi, E., and Aoki, N.: Gastric lesions of familial polyposis of the colon, Nihon Shokaki Byo Gakukai Zasshi (Jap. J. Gastroenterol.) 71: 86–95, 1974 (in Japanese).Google Scholar
  22. 22.
    Yamada, S., and Takahashi, T.: Familial polyposis of the large intestine, Gan no Rinsho (Jap. J. Cancer clin.) 17: 676–686, 1971 (in Japanese).PubMedGoogle Scholar

Copyright information

© The Japan Surgical Society 1974

Authors and Affiliations

  • Keiichi Ohsato
    • 1
    • 2
    • 3
  • Hidenobu Watanabe
    • 1
    • 2
    • 3
  • Hideaki Itoh
    • 1
    • 2
    • 3
  • Tsuneyoshi Yao
    • 1
    • 2
    • 3
  • Masaya Nishimura
    • 1
    • 2
    • 3
  1. 1.Department of Surgery IKyushu University Faculty of MedicineFukuokaJapan
  2. 2.Department of Pathology IIKyushu University Faculty of MedicineFukuokaJapan
  3. 3.Department of Internal Medicine IIKyushu University Faculty of MedicineFukuokaJapan

Personalised recommendations