Summary
C22 and C30 alkyl chains were attached to a silica hydride surface by a hydrosolation reaction. In each case both moieties were successfully bonded by either metal complex catalysis or free radical initiation. Carbon analysis, DRIFT spectra and13C CP-MAS NMR spectra confirm the bonding of the olefin to silica hydride. Conditions for maximum coverage were determined by a simplex procedure. Chromatographic evaluation of these long chain bonded phases was accomplished by separations of several types of mixtures: alkyl substituted benzenes; polycyclic aromatic hydrocarbons; carotenoids, tocopherols; tricyclic antidepressants; and peptides. The C30 column proved significantly better for separating the carotenoid and antidepressant mixtures and somewhat better for the peptide sample.
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Pesek, J.J., Matyska, M.T. & Takhar, S. Synthesis and characterization of long chain alkyl stationary phases on a silica hydride surface. Chromatographia 48, 631–636 (1998). https://doi.org/10.1007/BF02467592
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DOI: https://doi.org/10.1007/BF02467592