Chromatographia

, Volume 47, Issue 7–8, pp 475–476 | Cite as

Identification of affinity ligands from peptide libraries and their applications

  • D. J. Hammond
Papers Presented at: Affinity Chromatography Conference, Cambridge (UK), July 1–3, 1997 Extendend abstract

Summary

Combinatorial peptide libraries may be screened to identify novel ligands for use in the affinity purification of proteins. Strategies for the screening of libraries are summarized and characterization of the interaction of a particular target protein (fibrinogen) with a ligand (FLLVPL) is described. Factors important for implementing an affinity resin in a production environment are highlighted.

Key Words

Affinity chromatography Combinatorial libraries Fibrinogen Peptides 

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Copyright information

© Friedr. Vieweg & Sohn Verlagsgesellschaft mbH 1998

Authors and Affiliations

  • D. J. Hammond
    • 1
  1. 1.Biological ResearchBayer Corp.ClaytonUSA

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