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An improved extraction of marrubiim fromMarrubium vulgare

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Summary

Marrubiin is the main active compound isolated fromM. vulgare, a medicinal plant used in folk medicine to cure several diseases. The present study shows that chitin, an abundant natural polymer, may be successfully in chromatography column to separate marrubiin from complex mixtures. The experimental procedure described here represents an efficient and rapid method to obtain such compound in high yield.

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References

  1. F. Balmé, Plantas Medicinais. Ed. Hemus Ltda., São Paulo, Brazil, 1982, p. 241.

    Google Scholar 

  2. C. A. Newall, L. A. Anderson, J. D. Phillipson, Herbal Medicines. The Pharmaceutical Press, London, 1996, p. 165.

    Google Scholar 

  3. V. Schlemper, A. Ribas, M. Nicolau, V. Cechinel Filho, Phystomedicine3, 211 (1996).

    CAS  Google Scholar 

  4. M. M. Souza, R. A. P. De Jesus, V. Cechinel Filho, V. Schlemper, Phytomedicine, in press.

  5. A. O. S. Savi, V. Schlemper, R. A. P. de Jesus, V. Cechinel Filho, XIV Simpósio de Plantas Medicinais do Brasil, Florianópolis- Brasil, M 049 (1996).

  6. M. S. Henderson, R. McCrindle, J. Chem. Soc. C 2014 (1969).

  7. G. Laonigro, R. Lanzetta, M. Parrili, M. Adinolfi, L. Mangoni, Gazz. Chim. Ital.109, 145 (1979).

    CAS  Google Scholar 

  8. J. Bruneton, Elementos de Fitoquímica y de Farmacognosia, Ed. Acriba S.A., Zaragoza-Sapin, 1991, p. 294.

    Google Scholar 

  9. G. W. Rigby, U.S. Patent, 2,072,771 (1936).

  10. O. C. Bagio, E. Stadler, M. C. M. Laranjeira, Rev. Quim. Ind.57, 672 (1989).

    Google Scholar 

  11. R. A. A. Muzzareli, O. Tubertini, Talanta16, 1571 (1969).

    Article  Google Scholar 

  12. J. Nahlik, I. Derdowska, W. Neugebauer, G. Kupryszeswski, Chem. Anal. (Warsaw)30, 39 (1985).

    CAS  Google Scholar 

  13. W. Knöss, B. Reuter, J. Zapp, Biochem. J. in press.

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Authors and Affiliations

  1. Núcleo de Investigações Químico-Farmacêuticas (NIQFAR)/FAQFAR, Universidade do Vale do Itajaí (UNIVALI), 88.302-202, Itajaí, SC, Brazil

    C. A. Rodrigues, A. O. S. Savi, V. Schlemper, F. Reynaud & V. Cechinel-Filho

Authors
  1. C. A. Rodrigues
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  2. A. O. S. Savi
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  3. V. Schlemper
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  4. F. Reynaud
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  5. V. Cechinel-Filho
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Rodrigues, C.A., Savi, A.O.S., Schlemper, V. et al. An improved extraction of marrubiim fromMarrubium vulgare . Chromatographia 47, 449–450 (1998). https://doi.org/10.1007/BF02466478

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  • DOI: https://doi.org/10.1007/BF02466478

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