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The reactivity of the spastic arteries

La réactivité des artères spastiques

Die Reaktivität der spastischen Arterien

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Summary

Spasm has been induced in baboons' larger cerebral arteries. Thereafter their reactivity to changes in PaCO2 has been measured by carefully controlled angiography.

The changes in calibre which have been observed are consistent with the idea that “spasm” is a state of altered reactivity which includes an increased sensitivity to the presumed sympathetic stimulus of rising PaCO2. This altered reactivity to PaCO2 changes may persist for at least a week.

Résumé

Les auteurs ont provoqué un spasme sur les grosses artères cérébrales des babouins. La réactivité de ces artères aux variations de PaCO2 fut ensuite étudiée à l'aide d'angiographies réalisées dans des conditions précises. Les modifications de calibre observées sont compatibles avec l'idée que le «spasme» représente un état de réactivité altérée comprenant une plus grande sensibilité au stimulus sympathique présumé de l'augmentation en PaCO2. Cette réactivité altérée aux variations PaCO2 peut persister pendant au moins une semaine.

Zusammenfassung

Experimentelle Untersuchung zur Frage des Gefäß-Spasmus nach Blut-Injektionen in die Cisterna magna. Es wurde gleichzeitig der Einfluß des veränderten PCO2 und des veränderten Blutdrucks bestimmt.

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Authors and Affiliations

  1. The Nuffield Institute of Comparative Medicine, The Zoological Society of London, Regent's Park, London, England

    G. du Boulay M.B., M.R.C.P.F.F.R., L. Symon, R. H. Ackerman, D. Dorsch, B. E. Kendall & S. H. Shah

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  1. G. du Boulay M.B., M.R.C.P.F.F.R.
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  2. L. Symon
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  3. R. H. Ackerman
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  4. D. Dorsch
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  5. B. E. Kendall
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  6. S. H. Shah
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du Boulay, G., Symon, L., Ackerman, R.H. et al. The reactivity of the spastic arteries. Neuroradiology 5, 37–39 (1973). https://doi.org/10.1007/BF02464628

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  • DOI: https://doi.org/10.1007/BF02464628

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