Abstract
A molecular theory of inbreeding involving interactions between zones of gametic recognition (ZRG) localized on the chromosomal sets of male and female gametes is developed. This theory accounts for inbreeding effects and heterosis and raises the problem of control of embryonic development and the biological validity of the inbreeding coefficient. The mathematical analysis of this interaction system with sib matings permits the estimation of viability depression in inbred organisms. The biological validity of the model is discussed.
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Biémont, C., Bouffette, A.R. & Bouffette, J. Théorie chromosimique de l'inbreeding: Modèle probabiliste. Bltn Mathcal Biology 36, 417–434 (1974). https://doi.org/10.1007/BF02464618
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DOI: https://doi.org/10.1007/BF02464618